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heartburn, diarrhea, and constipation. Uncommon side effects are drowsiness, skin reactions, and headache. Some glucosamine products do not contain the labeled amount of glucosamine or contain excessive amounts of manganese. Ask your healthcare professional about reliable brands.
Some preliminary research suggests that glucosamine sulfate might raise blood sugar in people with diabetes. However, more reliable research indicates that glucosamine sulfate does not seem to significantly affect blood sugar control in people with type 2 diabetes. Glucosamine with routine blood sugar monitoring appears to be safe for most people with diabetes.
There is some concern that glucosamine products might cause allergic reactions in people who are sensitive to shellfish. Glucosamine is produced from the shells of shrimp, lobster, and crabs. But allergic reactions in people with shellfish allergy are caused by the meat of shellfish, not the shell. There are no reports of allergic reactions to glucosamine in people who are allergic to shellfish. There is also some information that people with shellfish allergy can safely take glucosamine products.
Do not take glucosamine if:
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.