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GENERIC NAME: GLIPIZIDE/METFORMIN - ORAL (GLIP-eh-zide/met-FOR-min)

BRAND NAME(S): Metaglip

Warning | Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage | Medical Alert

WARNING: The metformin in this combination medication can rarely cause a condition called lactic acidosis, which can be fatal. If you develop any of the following symptoms of lactic acidosis, stop this medication and seek immediate medical attention: unusual tiredness (fatigue) or severe drowsiness, low body temperature, unexplained muscle pain, breathing trouble or rapid breathing, unusually slow or irregular heartbeat. Lactic acidosis is more likely to occur in patients who have: serious infection, surgery, kidney or liver disease, conditions that may cause a low oxygen blood level or poor circulation (e.g., severe congestive heart failure, recent heart attack or stroke), excessive alcohol use, a lack of body fluids (dehydration), x-ray or scanning procedures that require an injectable iodinated contrast drug. The elderly are also at a higher risk, especially if you are over 80 years of age and have not had kidney and liver tests.

USES: This combination medication is used along with a diet and exercise program to control high blood sugar in diabetic patients. It works by releasing more of the insulin that your body naturally produces into your bloodstream and by helping your body use the insulin more effectively. Controlling high blood sugar helps prevent heart disease, strokes, kidney disease, blindness and circulation problems, as well as sexual function problems (impotence).

HOW TO USE: Take this medication by mouth, usually once or twice daily with a meal, or as directed by your doctor. Use this medication regularly in order to get the most benefit from it. Remember to use it at the same time(s) each day. Dosage is based on your medical condition and response to therapy. Read the patient information leaflet provided by your pharmacist. If you have any questions regarding the information, ask your doctor or pharmacist.




Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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glipizide/metformin-oral, Metaglip

What is a stroke?

A stroke, or cerebrovascular accident (CVA), occurs when blood supply to part of the brain is disrupted, causing brain cells to die. When blood flow to the brain is impaired, oxygen and glucose cannot be delivered to the brain. Blood flow can be compromised by a variety of mechanisms.

Blockage of an artery

  • Narrowing of the small arteries within the brain can cause a so-called lacunar stroke, (lacune=empty space). Blockage of a single arteriole can affect a tiny area of brain causing that tissue to die (infarct).
  • Hardening of the arteries (atherosclerosis) leading to the brain. There are four major blood vessels that supply the brain with blood. The anterior circulation of the brain that controls most motor, activity, sensation, thought, speech, and emotion is supplied by the carotid arteries. The posterior circulation, which supplies the brainstem and the cerebellum, con...

Read the Stroke article »




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