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I have been taking medications for open angle glaucoma for eighteen years. Over the period, i have used: 1st, TIMOPTOL in combination with Pilocapine eye drops. I used the drugs for about two years before I reacted to the timoptol. It lowered my heart rate to about 53 beats per minute. I infact experienced drop beats and was hospitalized. I then started on the combination of Betoptic, Pilocapine, and Diamox. I again reacted to Diamox. Thereafter, I was placed on Betoptic in combination with Pilocarpine and Xalatan. My eye pressure came to as low as between levels 8 and 14. In July/ Aug. 2009, My Doctor stopped my Pilocarpine. I am now on the combination of Travatan and Trusopt. The effect of my having to stop Pilocarpine is that I now use eye glasses for my sight, having lost my focus on both far and near objects because of my slow heart rate, my doctor now says I should stop Betoptic. I am reluctant to drop Betoptic, so I now have reduced my dosage of it to one drop per day. When I attended my clinic last earlier this month, my eye pressure was 15 in both eyes. I have been on the eye drops mainly, since I was diagnosed with the eye condition 18 years ago. The drugs are ok, but I strongly suggest that for every new patient special attention should be placed on the individual's pulse rate to avoid my type of experience. Published: March 01 ::