Melissa Conrad Stöppler, MD, is a U.S. board-certified Anatomic Pathologist with subspecialty training in the fields of Experimental and Molecular Pathology. Dr. Stöppler's educational background includes a BA with Highest Distinction from the University of Virginia and an MD from the University of North Carolina. She completed residency training in Anatomic Pathology at Georgetown University followed by subspecialty fellowship training in molecular diagnostics and experimental pathology.
Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.
In many cases genital warts do not cause any symptoms, but they are sometimes
associated with itching, burning, or tenderness. They may result in localized
irritation, depending upon their anatomic location. Women who have genital warts
inside the vagina may experience bleeding following sexual intercourse or an
abnormal vaginal discharge. Rarely, bleeding or urinary obstruction may occur if
the wart involves the urethral opening.
How is HPV infection diagnosed?
HPV sometimes can be suspected by changes that
appear on a Pap smear, since pap
smears identify infected abnormal cells that may be precursors to cancer. While
HPV infection can lead to precancerous changes in the cervix that are recognized
on the Pap smear, the Pap smear itself cannot definitely establish the diagnosis
of HPV infection, unless special testing is carried out on the material obtained from the
Pap smear. When there is
an abnormal Pap smear, the doctor often will do advanced testing on the material
to determine if, and which kind, of HPV may be present. HPV also can be detected
if a biopsy (for example, from a genital wart or from the uterine cervix) is
sent to the laboratory for analysis.
Is there a DNA test for types of HPV infection?
In 2009, the U.S. FDA approved the first DNA
tests for diagnosis of the common cancer-causing HPV types in cervical samples.
Two tests known as Cervista HPV
16/18 and Cervista HPV HR, are used to diagnose the presence of DNA from the
two most common HPV types associated with cancer, HPV 16 and 18, and all "high
risk" or cancer-associated HPV types, respectively. These tests do not replace
standard Pap testing or clinical examination and are used in combination with
traditional screening methods to help estimate a woman's risk and aid in
management decisions.
Sexually transmitted diseases, or STDs,
are infections that are transmitted during any type of sexual exposure,
including intercourse (vaginal or anal), oral sex, and the sharing of sexual
devices, such as vibrators. Women can contract all of the STDs, but may have no symptoms, or have different symptoms than men do.
Cervical cancer is cancer of the entrance to the womb (uterus). Regular pelvic exams and Pap testing can detect precancerous changes in the cervix. Precancerous changes in the cervix may be treated with cryosurgery, cauterization, or laser surgery. The most common symptom of cancer of the cervix is abnormal bleeding.
The term oral cancer includes cancer of the mouth (oral cavity) and the back of the mouth (oropharynx). Red and white patches inside the mouth, bleeding, loose teeth, pain upon swallowing, a lump in the neck, earache, and a sore on your lip or in your mouth that won't heal are all symptoms of oral cancer. Treatment for oral cancer depends upon the staging of the disease and usually involves surgery, radiation therapy, or chemotherapy.
Vaginitis is any type of vaginal infection or inflammation. The six most common types of vaginitis are Candida (yeast infections), bacterial vaginosis, trichomoniasis vaginitis, chlamydia vaginitis, viral vaginitis, and noninfectious vaginitis. Symptoms include itching, burning, and abnormal vaginal discharge. Treatment is different for each type of vaginitis.
Sexually transmitted diseases, or STDs, are infections that are transmitted during any
type of sexual exposure, including intercourse (vaginal or anal), oral sex, and
the sharing of sexual devices, such as vibrators. Although treatment exists for many STDs, others currently are
usually incurable, such as those caused by HIV, HPV, hepatitis B and C, and HHV-8.
Anal cancer, cancer located at the end of the large intestine, has symptoms that include anal or rectal bleeding, anal pain or pressure, anal discharge or itching, a change in bowel movements, and/or a lump in the anal region. Treatment for anal cancer may involve radiation, chemotherapy, or surgery and depends upon the stage of the cancer, its location, whether cancer is eradicated after the first treatment, and whether the patient has HIV.
Signs and symptoms of penile cancer include a lump on the penis and redness, irritation, or a sore on the penis. Risk of penis cancer is higher in uncircumcised men, due to a higher risk of HPV infection. Other risk factors include being over 60, having phimosis, having poor hygiene, using tobacco products, and having many sex partners. Prognosis and treatment depend upon the tumor's location and size, the stage of the cancer, and whether the cancer was recently diagnosed or if it recurred.
Vaginal cancer is fairly uncommon. There are two types of vaginal cancer: squamous cell carcinoma and adenocarcinoma. Risk factors include being 60 or older, exposure to DES while in the womb, HPV infection, and having a history of abnormal cervical cells. Painful intercourse, pelvic pain, vaginal lumps, and abnormal vaginal bleeding or discharge are all symptoms of vaginal cancer. Treatment depends upon the stage of the vaginal cancer and may involve surgery, radiation therapy, chemotherapy, and the use of radiosensitizers.
The HPV virus (genital warts) in men can cause health problems. Genital warts are confined primarily to the moist skin of the genitals or around the anus. Genital warts are caused by the human papillomaviruses (HPVs), which are transmitted through sexual contact.
Syphilis, a sexually transmitted disease, is caused by a microscopic, wormlike bacterial organism called a spirochete. There are three stages of syphilis. The first involves the formation of the chancre. The second stage often includes hair loss, a sore throat, white patches in the nose, mouth, and vagina, fever, headaches, and a skin rash. The third stage can cause extensive damage to the internal organs and the brain, and can lead to death. Though early infection often resolves on its own, treatment usually varies based on the stage of the infection at the time of diagnosis.
Sexual health information including birth control, impotence, herpes, sexually transmitted diseases, staying healthy, women's sexual health concerns, and men's sexual health concerns. Learn about the most common sexual conditions affecting men and women.
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