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February 10, 2012

Genital Warts (HPV) Glossary of Terms

The following are health and medical definitions of terms that appear in the Genital Warts (HPV) article.

Abnormal: Not normal. Deviating from the usual structure, position, condition, or behavior. In referring to a growth, abnormal may mean that it is cancerous or premalignant (likely to become cancer).

Abstinence: The voluntary self-denial of food, drink, or sex. Today, abstinence most commonly refers to denial of one's sexual activity.

Analysis: A psychology term for processes used to gain understanding of complex emotional or behavioral issues.

Anesthetic: A substance that causes lack of feeling or awareness. A local anesthetic causes loss of feeling in a part of the body. A general anesthetic puts the person to sleep.

Anogenital tract: Angiogenital tract is a term used to refer to both the anus and genital tract. The genital tract encompasses the external and internal sex organs in both men and women. The term anogenital tract is often used in the categorization and/or description of disease processes that can affect both of these anatomic regions. For example, infection with certain types of human papillomaviruses (HPVs) is associated with the development of cancers of the anogenital tract (cancers of the anus as well as cancers of the genital organs).

Anus: The opening of the rectum to the outside of the body.
See the entire definition of Anus

Asymptomatic: Without symptoms. For example, an asymptomatic infection is an infection with no symptoms.

Benign: Not cancer. Not malignant. A benign tumor does not invade surrounding tissue or spread to other parts of the body. A benign tumor may grow but it stays put (in the same place).
See the entire definition of Benign

Biopsy: The removal of a sample of tissue for purposes of diagnosis. (Many definitions of "biopsy" stipulate that the sample of tissue is removed for examination under a microscope. This may or may not be the case. The diagnosis may be achieved by other means such as by analysis of chromosomes or genes.)
See the entire definition of Biopsy

Birth control: Birth control is the use of any practices, methods, or devices to prevent pregnancy from occurring in a sexually active woman. Also referred to as family planning, pregnancy prevention, fertility control, or contraception; birth control methods are designed either to prevent fertilization of an egg or implantation of a fertilized egg in the uterus.
See the entire definition of Birth control

Bumps: The raised area of a bump or bruise results from blood leaking from these injured blood vessels into the tissues as well as from the body's response to the injury. A purplish, flat bruise that occurs when blood leaks out into the top layers of skin is referred to as an ecchymosis.

Cancer: An abnormal growth of cells which tend to proliferate in an uncontrolled way and, in some cases, to metastasize (spread).
See the entire definition of Cancer

Cervical: Having to do with any kind of neck including the neck on which the head is perched and the neck of the uterus. The word "cervix" in Latin means "neck". That is why cervical vertebrae and cervical cancer involve quite disparate parts of the anatomy joined only by the meaning of the word "cervix".

Cervical cancer: Cancer of the entrance to the womb (uterus). The cervix is the lower, narrow part of the uterus (womb). The uterus, a hollow, pear-shaped organ, is located in a woman's lower abdomen, between the bladder and the rectum. The cervix forms a canal that opens into the vagina, which leads to the outside of the body.

Regular pelvic exams and Pap testing can detect precancerous changes in the cervix. Precancerous changes in the cervix may be treated with cryosurgery, cauterization, or laser surgery. The most common symptom of cancer of the cervix is abnormal bleeding. Cancer of the cervix can be diagnosed using a Pap test or other procedures that sample the cervix tissue. Cancer of the cervix requires different treatment than cancer that begins in other parts of the uterus.
See the entire definition of Cervical cancer

Cervix: The cervix is the lower, narrow part of the uterus (womb). The uterus, a hollow, pear-shaped organ, is located in a woman's lower abdomen, between the bladder and the rectum. The cervix forms a canal that opens into the vagina, which leads to the outside of the body.


See the entire definition of Cervix back to top

Conization: Surgery to remove a cone-shaped piece of tissue from the cervix and cervical canal. Conization may be used to diagnose or treat a cervical condition. Also called cone biopsy.

Contrast: Short for "contrast media." Contrast media are X-ray dyes used to provide contrast, for example, between blood vessels and other tissue.

Cryotherapy: Literally, "cold therapy." Cryotherapy, sometimes referred to as cryosurgery, is a procedure used to destroy tissue of both benign and malignant lesions by the freezing and re-thawing process. Liquid nitrogen is the most commonly used freezing source for cryotherapy. Examples of the uses of cryotherapy in medicine are the treatment (removal) of various types of skin lesions , the treatment of dysplastic (precancerous) tissue of the uterine cervix, and the treatment of some prostate cancers.
See the entire definition of Cryotherapy

Cure: 1. To heal, to make well, to restore to good health. Cures are easy to claim and, all too often, difficult to confirm.
2. A time without recurrence of a disease so that the risk of recurrence is small, as in the 5-year cure rate for malignant melanoma.
3. Particularly in the past, a course of treatment. For example, take a cure at a spa.
See the entire definition of Cure

Diagnosis: 1 The nature of a disease; the identification of an illness. 2 A conclusion or decision reached by diagnosis. The diagnosis is rabies. 3 The identification of any problem. The diagnosis was a plugged IV.
See the entire definition of Diagnosis

Discharge: 1.The flow of fluid from part of the body, such as from the nose or vagina.
2. The passing of an action potential, such as through a nerve or muscle fiber.
3. The release of a patient from a course of care. The doctor may then dictate a discharge summary.

DNA: Deoxyribonucleic acid. One of two types of molecules that encode genetic information. (The other is RNA. In humans DNA is the genetic material; RNA is transcribed from it. In some other organisms, RNA is the genetic material and, in reverse fashion, the DNA is transcribed from it.)
See the entire definition of DNA

Dysplasia: Abnormal in form. From the Greek dys- (bad, disordered, abnormal) and plassein (to form). For example, retinal dysplasia is abnormal formation of the retina during embryonic development.

Epinephrine: A substance produced by the medulla (inside) of the adrenal gland. The name epinephrine was coined in 1898 by the American pharmacologist and physiologic chemist (biochemist) John Jacob Abel who isolated it from the adrenal gland which is located above (epi-) the kidney ("nephros" in Greek). (Abel also crystallized insulin). Technically speaking, epinephrine is a sympathomimetic catecholamine. It causes quickening of the heart beat, strengthens the force of the heart's contraction, opens up the airways (bronchioles) in the lungs and has numerous other effects. The secretion of epinephrine by the adrenal is part of the fight-or-flight reaction. Adrenaline is a synonym of epinephrine and is the official name in the British Pharmacopoeia.

Excision: 1. Surgical removal, as in the excision of a tumor. 2. The removal as if by surgery, as in base excision repair.
See the entire definition of Excision

FDA: The Food and Drug Administration, an agency within the U.S. Public Health Service, which is a part of the Department of Health and Human Services.
See the entire definition of FDA

Genetic: Having to do with genes and genetic information.

Genital: Pertaining to the external and internal organs of reproduction. (Not to be confused with genetic.)

Genital wart: A wart in the moist skin of the genitals or around the anus. Genital warts are due to a human papillomavirus (HPV). The HPVs, including those that cause genital warts, are transmitted through sexual contact. HPV can also be transmitted from mother to baby during childbirth. Most people infected with HPV have no symptoms, but these viruses increase a woman's risk for cancer of the cervix. HPV infection is the most common sexually transmitted disease in the US. It is also the leading cause of abnormal PAP smears and pre-cancerous changes of the cervix in women. There is no cure for HPV infection, although anti-viral medications can reduce outbreaks and topical preparations can speed healing. Once contracted, the virus can stay with a person for life. Also called condyloma acuminatum, condylomata.

HPV: See: Human papillomavirus.

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Immune: Protected against infection. The Latin immunis means free, exempt.

Immune system: A complex system that is responsible for distinguishing us from everything foreign to us, and for protecting us against infections and foreign substances. The immune system works to seek and kill invaders.
See the entire definition of Immune system

Immunity: The condition of being immune. Immunity can be innate (for example, humans are innately immune to canine distemper) or conferred by a previous infection or immunization.

Incidence: The frequency with which something, such as a disease, appears in a particular population or area. In disease epidemiology, the incidence is the number of newly diagnosed cases during a specific time period. The incidence is distinct from the prevalence which refers to the number of cases alive on a certain date.

Infant: A child up to 2 years (24 months) of age.
See the entire definition of Infant

Infection: The growth of a parasitic organism within the body. (A parasitic organism is one that lives on or in another organism and draws its nourishment therefrom.) A person with an infection has another organism (a "germ") growing within him, drawing its nourishment from the person.
See the entire definition of Infection

Infectivity: The proportion of persons exposed to an infectious agent who become infected by it.

Interferon: A naturally occurring substance that interferes with the ability of viruses to reproduce. Interferon also boosts the immune system.
See the entire definition of Interferon

Itching: An uncomfortable sensation in the skin that feels as if something is crawling on the skin or in the skin, and makes the person want to scratch the affected area.
See the entire definition of Itching

Laboratory: A place for doing tests and research procedures and preparing chemicals, etc. Although "laboratory" looks very like the Latin "laboratorium" (a place to labor, a work place), the word "laboratory" came from the Latin "elaborare" (to work out, as a problem, and with great pains), as evidenced by the Old English spelling "elaboratory" designating "a place where learned effort was applied to the solution of scientific problems."

Laser: A powerful beam of light that can produce intense heat when focused at close range. Lasers are used in medicine in microsurgery, cauterization, for diagnostic purposes, etc. For example, lasers are employed in microsurgery to cut tissue and remove tissue.
See the entire definition of Laser

Laser surgery: A type of surgery that uses the cutting power of a laser beam to make bloodless cuts in tissue or remove a surface lesion such as a skin tumor. There are a number of different types of lasers that differ in emitted light wavelengths and power ranges and in their ability to clot, cut, or vaporize tissue. Among the commonly used lasers are the pulsed-dye laser, the YAG laser, the CO2 (carbon dioxide) laser, the argon laser, the excimer laser, the KTP laser, and the diode laser.

Latent: Hidden, dormant, inactive.
See the entire definition of Latent

Lesion: Pronounced "lee-sion" with the emphasis on the "lee," a lesion can be almost any abnormality involving any tissue or organ due to any disease or any injury.
See the entire definition of Lesion

Liquid nitrogen: Nitrogen in a liquid state. Liquid nitrogen is supercool -- about 200 degrees Celsius (320 degrees Fahrenheit) below zero -- and is used for cryopreservation, cryosurgery, and cryomedicine.
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Microscope: An optical instrument that augments the power of the eye to see small objects. The name microscope was coined by Johannes Faber (1574-1629) who in 1628 borrowed from the Greek to combined micro-, small with skopein, to view. Although the first microscopes were simple microscopes, most (if not all) optical microscopes today are compound microscopes.

Neck: The part of the body joining the head to the shoulders. Also, any narrow or constricted part of a bone or organ that joins its parts as, for example, the neck of the femur bone.

Nitrogen: Element number 7, a colorless, odorless, tasteless gas that is biologically important. Nitrogen is a constituent of protein and nucleic acids and is present in all living cells. Nitrogen does not support respiration and is fatal if breathed alone, because of the lack of oxygen. Nitrogen is soluble in the blood and body fluids and, when released as bubbles of gas, can have serious or even fatal consequences.
See the entire definition of Nitrogen

Obstruction: Blockage of a passageway. See, for example: Airway obstruction; Intestinal obstruction.

Pap Smear: A screening test for cervical cancer based on the examination under the microscope of cells collected from the cervix, smeared on a slide and specially stained to reveal premalignant (before cancer) and malignant (cancer) changes as well as changes due to noncancerous conditions such as inflammation from infections.
See the entire definition of Pap Smear

Penile: Of or pertaining to the penis.

Precancerous: Pertaining to something that is not yet overtly cancerous, but appears to be on its way to becoming a cancer. Synonymous with premalignant.

Recur: To occur again. To return. Any symptom (such as fatigue), any sign (such as a heart murmur), or any disease can recur.

Sexually transmitted disease: Any disease transmitted by sexual contact; caused by microorganisms that survive on the skin or mucus membranes of the genital area; or transmitted via semen, vaginal secretions, or blood during intercourse. Because the genital areas provide a moist, warm environment that is especially conducive to the proliferation of bacteria, viruses, and yeasts, a great many diseases can be transmitted this way. They include AIDS, chlamydia, genital herpes, genital warts, gonorrhea, syphilis, yeast infections, and some forms of hepatitis. Also known as a morbus venereus or venereal disease.
See the entire definition of Sexually transmitted disease

STD: Sexually transmitted disease.

Substance: 1. Material with particular features, as a pressor substance.
2. The material that makes up an organ or structure. Also known in medicine as the substantia.
3. A psychoactive drug as, for example, in substance abuse.

Surgery: The word "surgery" has multiple meanings. It is the branch of medicine concerned with diseases and conditions which require or are amenable to operative procedures. Surgery is the work done by a surgeon. By analogy, the work of an editor wielding his pen as a scalpel is s form of surgery. A surgery in England (and some other countries) is a physician's or dentist's office.
See the entire definition of Surgery

Therapy: The treatment of disease.
See the entire definition of Therapy

Urinary: Having to do with the kidneys, ureters, and bladder. The urinary system represents the functional and anatomic aspects of the kidneys, ureters, and bladder.

Vagina: The muscular canal extending from the cervix to the outside of the body. It is usually six to seven inches in length, and its walls are lined with mucus membrane. It includes two vaultlike structures, the anterior (front) vaginal fornix and the posterior (rear) vaginal fornix. The cervix protrudes slightly into the vagina, and it is through a tiny hole in the cervix (the os) that sperm make their way toward the internal reproductive organs. The vagina also includes numerous tiny glands that make vaginal secretions.
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Vaginal discharge: Vaginal discharge is a fluid produced by glands in the vaginal wall and cervix that drains from the opening of the vagina. The amount and appearance of normal vaginal discharge varies throughout the menstrual cycle. An increase in the amount of vaginal discharge, an abnormal odor or consistency of the fluid, or pain that accompanies vaginal discharge can all be signs of infection or other disorders. Such disorders include (this is not an all inclusive list) bacterial vaginosis, yeast vaginitis, and vaginitis.

Venereal: Having to do with sexual contact. The word venereal comes from Venus, the Roman goddess of love. A venereal disease (morbus venereus) is contracted and transmitted by sexual contact. Today the more common term is sexually transmitted, as in a sexually transmitted infection and sexually transmitted disease.

Viral: Of or pertaining to a virus. For example, "My daughter has a viral rash."

Viral infection: Infection caused by the presence of a virus in the body. Depending on the virus and the person's state of health, various viruses can infect almost any type of body tissue, from the brain to the skin. Viral infections cannot be treated with antibiotics; in fact, in some cases the use of antibiotics makes the infection worse. The vast majority of human viral infections can be effectively fought by the body's own immune system, with a little help in the form of proper diet, hydration, and rest. As for the rest, treatment depends on the type and location of the virus, and may include anti-viral or other drugs.

Virus: A microorganism smaller than a bacteria, which cannot grow or reproduce apart from a living cell. A virus invades living cells and uses their chemical machinery to keep itself alive and to replicate itself. It may reproduce with fidelity or with errors (mutations)-this ability to mutate is responsible for the ability of some viruses to change slightly in each infected person, making treatment more difficult.
See the entire definition of Virus

Wart: A local growth of the outer layer of the skin (the epidermis) caused by a virus. The virus of warts (a papillomavirus) is transmitted by contact. The contact can be with a wart on someone else or one on oneself (autoinoculation).
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  • Related Diseases & Conditions

    • Sexually Transmitted Diseases in Women (STDs)
      • Sexually transmitted diseases, or STDs, are infections that are transmitted during any type of sexual exposure, including intercourse (vaginal or anal), oral sex, and the sharing of sexual devices, such as vibrators. Women can contract all of the STDs, but may have no symptoms, or have different symptoms than men do.
    • Cervical Cancer
      • Cervical cancer is cancer of the entrance to the womb (uterus). Regular pelvic exams and Pap testing can detect precancerous changes in the cervix. Precancerous changes in the cervix may be treated with cryosurgery, cauterization, or laser surgery. The most common symptom of cancer of the cervix is abnormal bleeding.
    • Oral Cancer
      • The term oral cancer includes cancer of the mouth (oral cavity) and the back of the mouth (oropharynx). Red and white patches inside the mouth, bleeding, loose teeth, pain upon swallowing, a lump in the neck, earache, and a sore on your lip or in your mouth that won't heal are all symptoms of oral cancer. Treatment for oral cancer depends upon the staging of the disease and usually involves surgery, radiation therapy, or chemotherapy.
    • Vaginitis
      • Vaginitis is any type of vaginal infection or inflammation. The six most common types of vaginitis are Candida (yeast infections), bacterial vaginosis, trichomoniasis vaginitis, chlamydia vaginitis, viral vaginitis, and noninfectious vaginitis. Symptoms include itching, burning, and abnormal vaginal discharge. Treatment is different for each type of vaginitis.
    • Sexually Transmitted Diseases in Men (STDs in Men)
      • Sexually transmitted diseases, or STDs, are infections that are transmitted during any type of sexual exposure, including intercourse (vaginal or anal), oral sex, and the sharing of sexual devices, such as vibrators. Although treatment exists for many STDs, others currently are usually incurable, such as those caused by HIV, HPV, hepatitis B and C, and HHV-8.
    • Anal Cancer
      • Anal cancer, cancer located at the end of the large intestine, has symptoms that include anal or rectal bleeding, anal pain or pressure, anal discharge or itching, a change in bowel movements, and/or a lump in the anal region. Treatment for anal cancer may involve radiation, chemotherapy, or surgery and depends upon the stage of the cancer, its location, whether cancer is eradicated after the first treatment, and whether the patient has HIV.
    • Penis Cancer
      • Signs and symptoms of penile cancer include a lump on the penis and redness, irritation, or a sore on the penis. Risk of penis cancer is higher in uncircumcised men, due to a higher risk of HPV infection. Other risk factors include being over 60, having phimosis, having poor hygiene, using tobacco products, and having many sex partners. Prognosis and treatment depend upon the tumor's location and size, the stage of the cancer, and whether the cancer was recently diagnosed or if it recurred.
    • Vaginal Cancer
      • Vaginal cancer is fairly uncommon. There are two types of vaginal cancer: squamous cell carcinoma and adenocarcinoma. Risk factors include being 60 or older, exposure to DES while in the womb, HPV infection, and having a history of abnormal cervical cells. Painful intercourse, pelvic pain, vaginal lumps, and abnormal vaginal bleeding or discharge are all symptoms of vaginal cancer. Treatment depends upon the stage of the vaginal cancer and may involve surgery, radiation therapy, chemotherapy, and the use of radiosensitizers.
    • Genital Warts in Men (HPV Virus)
      • The HPV virus (genital warts) in men can cause health problems. Genital warts are confined primarily to the moist skin of the genitals or around the anus. Genital warts are caused by the human papillomaviruses (HPVs), which are transmitted through sexual contact.
    • Syphilis In Women
      • Syphilis, a sexually transmitted disease, is caused by a microscopic, wormlike bacterial organism called a spirochete. There are three stages of syphilis. The first involves the formation of the chancre. The second stage often includes hair loss, a sore throat, white patches in the nose, mouth, and vagina, fever, headaches, and a skin rash. The third stage can cause extensive damage to the internal organs and the brain, and can lead to death. Though early infection often resolves on its own, treatment usually varies based on the stage of the infection at the time of diagnosis.
    • Sexual Health
      • Sexual health information including birth control, impotence, herpes, sexually transmitted diseases, staying healthy, women's sexual health concerns, and men's sexual health concerns. Learn about the most common sexual conditions affecting men and women.
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Genital Warts (HPV)

What is the HPV vaccine?

The vaccine, Gardasil, is the first vaccine developed to prevent cervical cancer, precancerous genital lesions, and genital warts due to HPV.

Who should get the HPV vaccine?

CDC recommends the HPV vaccine for all 11 and 12 year old girls. The recommendation allows for vaccination to begin at age nine. Vaccination also is recommended for females aged 13 through 26 years who have not been previously vaccinated or who have not completed the full series of shots.

Are there other HPV vaccines in development?

Another HPV vaccine (being developed by GlaxoSmithKline) is in the final stages of clinical testing, but it is not yet licensed. This vaccine would protect against the two types of HPV that cause most cervical cancers.

How and when is the vaccine delivered?

The vaccine is given in a series of three injections over a six-month period. ...

Read the Gardasil HPV Vaccine article »






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