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February 10, 2012
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gemtuzumab ozogamicin - injection, Mylotarg

GENERIC NAME: GEMTUZUMAB OZOGAMICIN - INJECTION (gem-TOOZ-oo-mab oh-zoh-GAM-ih-sin)

BRAND NAME(S): Mylotarg

Warning | Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage

WARNING: This medication will cause very serious blood disorders (decreased bone marrow function leading to low number of blood cells such as white cells, red cells, and platelets). This effect can decrease your body's ability to fight an infection, cause anemia, or cause your body to bruise or bleed more easily. Tell your doctor immediately if you develop any of the following symptoms: signs of infection (e.g., fever, persistent sore throat), easy bruising/bleeding, unusual tiredness, fast/pounding heartbeat.

This medication may cause a very serious (infrequently fatal) allergic reaction or breathing problems. In most cases, these reactions occurred while the medication was being given or within 24 hours, and the symptoms usually went away afterward. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction or breathing problem, including rash, itching, swelling, severe dizziness, shortness of breath, or trouble breathing.

This medication may also cause very serious (possibly fatal) liver disease. Tell your doctor immediately if you develop symptoms of liver disease, including persistent nausea/vomiting, yellowing skin/eyes, sudden weight gain, or severe stomach/abdominal pain.

USES: This medication is used to treat a certain type of leukemia (acute myeloid leukemia-AML). It is recommended for use in patients whose AML has returned for the first time and who are 60 years or older and cannot use other forms of cancer chemotherapy. This medication works by stopping the growth of cancer cells.




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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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gemtuzumab ozogamicin - injection, Mylotarg

Leukemia facts

  • Leukemia is a cancer of the blood cells.
  • While the exact cause(s) of leukemia is not known, risk factors have been identified.
  • Leukemias are grouped by how quickly the disease develops (acute or chronic) as well as by the type of blood cell that is affected (lymphocytes or myelocytes). The four main types of leukemia include acute lymphocytic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myelocytic leukemia (AML), and chronic myelocytic leukemia (CML).
  • People with leukemia are at significantly increased risk for developing infections, anemia, and bleeding. Other symptoms and signs include easy bruising, weight loss, night sweats, and unexplained fevers.
  • The diagnosis of leukemia is supported by findings of the medical history and examination, and examining blood and bone marrow samples under a microscope.

  • Tre...

Read the Leukemia article »


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