GENERIC NAME: GEMTUZUMAB OZOGAMICIN - INJECTABLE (gem-TOOZ-oo-mab oh-zoh-GAM-ih-sin)
BRAND NAME(S): Mylotarg
Warning | Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage | Medical Alert
WARNING: This is a potent medication that can lower the body's ability to fight infection. Notify your doctor promptly if you develop any signs of an infection such as fever, chills, or persistent sore throat. Avoid having immunizations/vaccinations and contact with people who are ill during your treatment. This drug may also cause severe, rarely fatal, allergic-type reactions and liver problems. Seek immediate medical attention if you experience any of the following allergic-type symptoms during your treatment with this drug: rash, severe itching, swelling, dizziness, trouble breathing. Also, tell your doctor immediately if you experience any of the following symptoms of severe liver problems during, or anytime after your treatment with this drug: unusual weight gain, stomach pain/swelling.
USES: Gemtuzumab ozogamicin is used to treat a certain form of leukemia called acute myeloid leukemia (AML). Leukemia is a form of cancer that affects the white blood cells. This medication works by combining an antibody that is specific for this form of leukemia with a potent anti-cancer antibiotic. It is recommended only for people with AML who are older than 60 years of age or who should not receive other forms of cancer chemotherapy.
HOW TO USE: Follow all instructions for proper mixing and dilution with the correct IV fluids. If you have questions regarding the use of this medication, consult your pharmacist. This medication must be protected from light (sunlight or fluorescent indoor light) at all times. Exposure of this drug to light may make it ineffective. Consult your pharmacist for details. Give this medication by vein (IV) over 2 hours in a saline solution (NS), usually once every 14 days for a total of 2 doses only; or as directed by your doctor. The dosage is based on your body size, medical condition, and response to therapy. It is recommended that other medications (acetaminophen, diphenhydramine) be given before, and up to 12 hours after this drug has been given to decrease the risk of certain allergic-like side effects (e.g., chills, fever). This medication may contain small particles after it is added to the IV solution. It is very important to use an IV filter (in- line filter) when giving this medication. Consult your pharmacist for the proper use of the filter. Before using, check this product visually for unusual particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard needles and medical supplies safely. Consult your pharmacist.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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