What is the dosage for gemfibrozil?
The recommended dose of gemfibrozil is 600 mg twice daily (30 minutes before breakfast and dinner).
Which drugs or supplements interact with gemfibrozil?
Gemfibrozil can cause problems when used together with the statin family of cholesterol-reducing medications, for example:
- lovastatin (Mevacor),
- pravastatin (Pravachol),
- simvastatin (Zocor),
- fluvastatin (Lescol),
- rosuvastatin (Crestor), and
- atorvastatin (Lipitor)
Gemfibrozil can increase the effect of the blood thinner, warfarin (Coumadin), and thus may lead to bleeding. Therefore, patients on warfarin may need to have their doses of warfarin reduced when starting gemfibrozil.
Colestipol (Colestid) and cholestyramine (Questran) reduce the absorption of gemfibrozil and reduce its effectiveness if taken at the same time. Therefore, gemfibrozil should be administered one hour before or 4-6 hours after administering colestipol or cholestyramine.
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