gemfibrozil, Lopid (cont.)

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PREPARATIONS: Tablets: 600 mg

STORAGE: Tablets should be stored at room temperature between 20 C – 25 C (68 F – 77 F).

PRESCRIBED FOR: Gemfibrozil is used for reducing elevated triglyceride levels that are high enough to cause pancreatitis. Because gemfibrozil raises HDL and decreases triglycerides it is prescribed for preventing coronary heart disease in individuals without a history or symptoms of coronary heart disease who have low HDL, high LDL and high triglycerides. Gemfibrozil is prescribed after other therapies have failed, and it is not intended for treating patients who only have low HDL. Gemfibrozil is used together with diet and exercise.

DOSING: The recommended dose of gemfibrozil is 600 mg twice daily (30 minutes before breakfast and dinner).

DRUG INTERACTIONS: Gemfibrozil, when used together with the statin family of cholesterol-reducing medications, for example, lovastatin (Mevacor), pravastatin (Pravachol), simvastatin (Zocor), fluvastatin (Lescol), rosuvastatin (Crestor), and atorvastatin (Lipitor) increases the risk of a condition called rhabdomyolysis (muscle injury) that when severe can lead to kidney damage and even death. Rhabdomyolysis may occur as early as three weeks or several months after starting combination therapy. The benefit of combining gemfibrozil with statins does not outweigh the risk of rhabdomyolysis.

Medically Reviewed by a Doctor on 10/29/2014

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