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Ganglion

Medical Author: William C. Shiel Jr., MD, FACP, FACR

Cyst Symptoms and Causes

Medical Author: Melissa Conrad Stöppler, MD
Medical Editor: William C. Shiel Jr., MD, FACP, FACR

Read about the causes and types of cysts.A cyst is a closed sac- or bladder-like structure that is not a normal part of the tissue where it is found. Cysts are common and can occur anywhere in the body in persons of any age. Cysts usually contain a gaseous, liquid, or semisolid substance. Cysts vary in size; they may be detectable only under a microscope or they can grow so large that they displace normal organs and tissues. The outer wall of a cyst is called the capsule.

Cysts can arise through a variety of processes in the body, including...

What is a ganglion?

A ganglion is a sac-like swelling or cyst formed from the tissue that lines a joint or tendon. The tissue, called synovium, normally functions to produce lubricating fluid for these areas. A ganglion is a cyst formed by the synovium that is filled with a thick jelly-like fluid. While ganglia can follow local trauma to the tendon or joint, they usually form for unknown reasons. Occasionally, ganglia are early signs of arthritis that will become more obvious in the future.

Where do ganglia form and what symptoms do they cause?

Ganglia can form around any joint, but they are most frequently found in the wrist and ankles. They are usually painless and often barely visible as localized swellings. They typically do not appear to be inflamed. The largest ganglions form behind the back of the knee, causing a sense of fullness or tightness. A ganglion here is referred to as a Baker cyst, after the doctor who originally described the condition.

How are ganglia treated?

A ganglion can spontaneously rupture and go away. Other treatment options include removal of the ganglion fluid with a needle and syringe (aspiration) with or without an injection of cortisone medication. Occasionally, the entire ganglion is resected with surgery. People with a persisting or recurring ganglion should be evaluated for signs of systemic forms of arthritis, such as rheumatoid arthritis.

For further information, please visit the Arthritis Center.

References:

Clinical Primer of Rheumatology, Lippincott Williams & Wilkens, edited by William Koopman, et al., 2003.

Kelley's Textbook of Rheumatology, W B Saunders Co, edited by Shaun Ruddy, et al., 2000.


Last Editorial Review: 1/28/2008




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Suggested Reading by Our Doctors
MedicineNet Doctors
  • Rheumatoid Arthritis - Learn more about rheumatoid arthritis, an autoimmune disease that causes chronic joint inflammation, which has symptoms that include stiffness, fever, muscle and joint aches, loss of appetite, and fatigue. Treatment of rheumatoid arthritis incorporates the use of first-line drugs (aspirin and corticosteroids for pain and inflammation) and second-line drugs (methotrexate and hydroxychloroquine to prevent joint destruction and promote remission).
  • Osteoarthritis - Osteoarthritis (OA or degenerative arthritis) is a joint disease caused by cartilage loss in a joint. Pain and stiffness are symptoms. Read about diagnosis and treatment.
  • Baker Cyst - Learn about Baker's cyst (popliteal cyst) causes, symptoms (knee pain, swelling), diagnosis and treatment (surgery).

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Ganglion

What is rheumatoid arthritis?

Rheumatoid arthritis (RA) is an autoimmune disease that causes chronic inflammation of the joints. Rheumatoid arthritis can also cause inflammation of the tissue around the joints, as well as in other organs in the body. Autoimmune diseases are illnesses that occur when the body's tissues are mistakenly attacked by their own immune system. The immune system is a complex organization of cells and antibodies designed normally to "seek and destroy" invaders of the body, particularly infections. Patients with autoimmune diseases have antibodies in their blood that target their own body tissues, where they can be associated with inflammation. Because it can affect multiple other organs of the body, rheumatoid arthritis is referred to as a systemic illness and is sometimes called rheumatoid disease.

While rheumatoid arthritis is a chronic illness, meaning it can last for years, patients may ex...

Read the Rheumatoid Arthritis article »










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