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February 9, 2012
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ganciclovir implant - intraocular, Vitrasert

GENERIC NAME: GANCICLOVIR IMPLANT - INTRAOCULAR (gan-SYE-klo-veer)

BRAND NAME(S): Vitrasert

Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage

USES: This medication is used in patients with AIDS (acquired immunodeficiency syndrome) to treat a serious infection of the eye called CMV (cytomegalovirus) retinitis. It works by stopping the growth of the virus. This medication is not a cure for CMV retinitis, but it helps to slow the course of the disease, which can lead to visual changes or loss of vision.

HOW TO USE: This medication is inserted into the affected eye(s) by a surgeon. Follow all instructions on what to do before and after surgery. The implant is designed to slowly release the medication into the eye over 5 to 8 months. The doctor will decide when the implant will need to be replaced.Tell your doctor if your condition does not improve, if it worsens, or if you have signs of the CMV affecting other parts of the body (e.g., cough, fever, shortness of breath, stomach/abdominal pain, diarrhea, leg pain/weakness, headaches, confusion).

SIDE EFFECTS: A temporary decrease in vision will usually occur after the surgery and last 2 to 4 weeks. If this effect persists or worsens, tell your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: other vision changes/loss, eye pain/swelling/redness, bleeding in or around the eye.A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.




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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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ganciclovir implant - intraocular, Vitrasert

What is the history of HIV, and when was HIV discovered?

The history of the human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) dates back to 1981, when homosexual men with symptoms of a disease that now are considered typical of AIDS were first described in Los Angeles and New York. The men had an unusual type of lung infection (pneumonia) called Pneumocystis carinii (now known as Pneumocystis jiroveci) pneumonia (PCP) and rare skin tumors called Kaposi's sarcomas. The patients were noted to have a severe reduction in a type of cell in the blood (CD4 cells) that is an important part of the immune system. These cells, often referred to as T cells, help the body fight infections. Shortly thereafter, this disease was recognized throughout the United States, Western Europe, and Africa. In 1983, researchers in the United States and France described the virus that causes AIDS, now known as HIV, belonging to t...

Read the Human Immunodeficiency Virus article »




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