Gamma Linolenic Acid
What other names is Gamma Linolenic Acid known by?
Acide Gammalinolénique, Acide Gamma-Linolénique, Ácido Gama Linolénico, AGL, Gamolenic Acid, GLA, Gammalinolenic Acid, Gamma-Linolenic Acid, (Z,Z,Z)-Octadeca-6,9,12-trienoic acid.
What is Gamma Linolenic Acid?
Gamma linolenic acid is a fatty substance found in various plant seed oils such as borage oil and evening primrose oil
. People use it as medicine.
Gamma linolenic acid (GLA) is used for conditions that affect the skin including systemic sclerosis
, and eczema
. It is also used for rheumatoid arthritis
), polyps in the mouth, high cholesterol
and other blood fats
, heart disease
, metabolic syndrome
(Syndrome-X), diabetic nerve pain
, attention deficit-hyperactivity
after childbirth, chronic fatigue syndrome
), and hay fever
). Some people use it to prevent cancer
and to help breast cancer
patients respond faster to treatment with the drug tamoxifen
Possibly Effective for...
- Nerve problems due to diabetes (diabetic neuropathy). Taking gamma linolenic acid by mouth for 6-12 months seems to reduce symptoms and prevent nerve damage in people with nerve pain due to type 1 or type 2 diabetes. Gamma linolenic acid seems to work better in people with good blood sugar control.
Possibly Ineffective for...
- Allergic skin conditions (eczema). Some early research suggests that taking gamma linolenic acid by mouth for 4 weeks might improve symptoms in children with allergic skin conditions such as itching and redness. However, combined results from 11 studies show that gamma linolenic acid from borage oil or evening primrose oil does not improve allergic skin conditions.
- Scleroderma, a condition in which skin hardens. Some research suggests that taking gamma linolenic acid by mouth does not reduce symptoms of scleroderma.
- Ulcerative colitis. Some research suggests that taking a combination of gamma linolenic acid, eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) for 12 months does not reduce symptoms of ulcerative colitis.
Insufficient Evidence to Rate Effectiveness for...
More evidence is needed to rate the effectiveness of gamma linolenic acid for these uses.
Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).