The following are health and medical definitions of terms that appear in the Gallstones article. Abdomen: The belly , that part of the body that contains all of the structures between the chest and the pelvis . The abdomen is separated anatomically from the chest by the diaphragm , the powerful muscle spanning the body cavity below the lungs .
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Abdominal: Relating to the abdomen, the belly , that part of the body that contains all of the structures between the chest and the pelvis . The abdomen is separated anatomically from the chest by the diaphragm , the powerful muscle spanning the body cavity below the lungs .
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Abdominal cavity: The cavity within the abdomen, the space between the abdominal wall and the spine.
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Abnormal: Not normal. Deviating from the usual structure, position, condition, or behavior. In referring to a growth, abnormal may mean that it is cancerous or premalignant (likely to become cancer ).
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Abscess: A local accumulation of pus anywhere in the body. The following are some examples of abscesses: - A skin abscess is better known as a common boil;
- A peritonsillar abscess is a persistent collection of pus behind the tonsils; and
- A perianal abscess is a pool of pus that forms next to the anus, often causing considerable tenderness and swelling in that area and pain on sitting down and on defecating.
Absorption: Uptake. In the biomedical sciences, absorption has diverse specific meanings.
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Access: 1. In general, a means of approaching something. 2. In health care, the opportunity or right to receive health care. 3. In dialysis, the point on the body where a needle or catheter is inserted to gain entry to the bloodstream.
Acute: Of abrupt onset, in reference to a disease. Acute often also connotes an illness that is of short duration, rapidly progressive, and in need of urgent care.
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Alanine: An amino acid, one of the 20 building blocks of protein. Alanine is not an "essential" amino acid. It is not essential to the diet, but can be made by the body from other substances. Alanine was discovered in protein in 1875. Symbol: Ala.
Alcoholism: Physical dependence on alcohol to the extent that stopping alcohol use will bring on withdrawal symptoms. In popular and therapeutic parlance, the term may also be used to refer to ingrained drinking habits that cause health or social problems. Treatment requires first ending the physical dependence, then making lifestyle changes that help the individual avoid relapse . In some cases, medication or hospitalization are needed. Alcohol dependence can have many serious effects on the brain , liver , and other organs of the body.
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Aminotransferase: An enzyme that catalyzes the transfer of an amino group from a donor molecule to a recipient molecule. The donor molecule is usually an amino acid while the recipient (acceptor) molecule is usually an alpha-2 keto acid. An aminotransferase is also called a transaminase. Two of the better known enzymes in this class are serum glutamic oxaloacetic transaminase (SGOT) and serum glutamic pyruvic transaminase (SGPT). Both of these transaminases (SGOT and SGPT) are normally found primarily in cells in the liver and heart, are released into the bloodstream as the result of liver or heart damage, and so are used as liver and heart tests.
Amylase: An enzyme produced in the pancreas and salivary glands that helps in the digestion of starches. Elevation of blood amylase is common in pancreatitis .
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Anesthesia: Loss of feeling or awareness. A general anesthetic puts the person to sleep. A local anesthetic causes loss of feeling in a part of the body such as a tooth or an area of skin without affecting consciousness. Regional anesthesia numbs a larger part of the body such as a leg or arm, also without affecting consciousness. The term "conduction anesthesia" encompasses both local and regional anesthetic techniques. Many surgical procedures can be done with conduction anesthesia without significant pain. In many situations, such as a C-section, conduction anesthesia is safer and therefore preferable to general anesthesia. However, there are also many types of surgery in which general anesthesia is clearly appropriate.
Angina: Chest pain due to an inadequate supply of oxygen to the heart muscle. The chest pain of angina is typically severe and crushing. There is a feeling just behind the breastbone (the sternum) of pressure and suffocation.
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Antibiotic: A drug used to treat infections caused by bacteria and other microorganisms. Originally, an antibiotic was a substance produced by one microorganism that selectively inhibits the growth of another. Synthetic antibiotics, usually chemically related to natural antibiotics, have since been produced that accomplish comparable tasks.
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Appendicitis: Inflammation of the appendix , the small worm-like projection from the first part of the colon . Appendicitis usually involves infection of the appendix by bacteria that invade it and infect the wall of the appendix. Appendicitis can progress to produce an abscess (a pocket of pus) and even peritonitis (inflammation of the lining of the abdomen and pelvis).
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AST: 1. Aspartate aminotransferase, an enzyme normally present in liver and heart cells. AST is released into blood when the liver or heart is damaged. The blood AST levels are thus elevated with liver damage (for example, from viral hepatitis) or with an insult to the heart (for example, from a heart attack). Some medications can also raise AST levels. AST is also known as serum glutamic oxaloacetic transaminase (SGOT). 2. Androgen suppression therapy. See: Androgen suppression.
Attention: The ability to focus selectively on a selected stimulus, sustaining that focus and shifting it at will. The ability to concentrate.
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Bacteria: Single-celled microorganisms which can exist either as independent (free-living) organisms or as parasites (dependent upon another organism for life).
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Belching: A normal process to relieve distention from the air that accumulates in the stomach. The upper abdominal discomfort associated with excessive swallowed air may extend into the lower chest, producing symptoms suggesting heart or lung disease.
Bile: Bile is a yellow-green fluid that is made by the liver, stored in the gallbladder and passes through the common bile duct into the duodenum where it helps digest fat. The principal components of bile are cholesterol, bile salts, and the pigment bilirubin.
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Bile acid: An acid made by the liver that works with bile to break down fats.
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Biliary: Having to do with the gallbladder , bile ducts , or bile. The biliary system itself consists of the gallbladder and bile ducts and, of course, the bile.
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Bilirubin: A yellow-orange compound produced by the breakdown of hemoglobin from red blood cells.
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Blood: The familiar red fluid in the body that contains white and red blood cells, platelets, proteins, and other elements. The blood is transported throughout the body by the circulatory system. Blood functions in two directions: arterial and venous. Arterial blood is the means by which oxygen and nutrients are transported to tissues while venous blood is the means by which carbon dioxide and metabolic by-products are transported to the lungs and kidneys, respectively, for removal from the body.
Blood pressure: The blood pressure is the pressure of the blood within the arteries. It is produced primarily by the contraction of the heart muscle. It's measurement is recorded by two numbers. The first (systolic pressure) is measured after the heart contracts and is highest. The second (diastolic pressure) is measured before the heart contracts and lowest. A blood pressure cuff is used to measure the pressure. Elevation of blood pressure is called "hypertension".
Bowel: Another name for the intestine . The small bowel and the large bowel are the small intestine and large intestine , respectively.
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Calcium: A mineral found mainly in the hard part of bones, where it is stored. Calcium is added to bones by cells called osteoblasts and is removed from bones by cells called osteoclasts. Calcium is essential for healthy bones. It is also important for muscle contraction, heart action, nervous system maintenance, and normal blood clotting. Food sources of calcium include dairy foods, some leafy green vegetables such as broccoli and collards, canned salmon, clams, oysters, calcium-fortified foods, and tofu. According to the National Academy of Sciences, adequate intake of calcium is 1,200 milligrams a day (four glasses of milk) for men and women 51 and older, 1,000 milligrams a day for adults 19 through 50, and 1,300 milligrams a day for children 9 through 18. The upper limit for calcium intake is 2.5 grams daily.
Calorie: A unit of food energy. In nutrition terms, the word calorie is used instead of the more precise scientific term kilocalorie which represents the amount of energy required to raise the temperature of a liter of water one degree centigrade at sea level. The common usage of the word calorie of food energy is understood to refer to a kilocalorie and actually represents, therefore, 1000 true calories of energy. A calorie is also known as cal, gram calorie, or small calorie.
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Cancer: An abnormal growth of cells which tend to proliferate in an uncontrolled way and, in some cases, to metastasize (spread).
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Cannula: Simply a slender tube that can be inserted into a body cavity or duct. During the insertion of the cannula, its lumen (interior) is usually occupied by a trocar, a solid shaft, to stiffen it. The word "cannula" is the diminutive of the Latin "canna" (reed) = a little reed.
CAT scan : Pictures of structures within the body created by a computer that takes the data from multiple X-ray images and turns them in pictures on a screen. The CAT (computerized axial tomography) scan can reveal some soft-tissue and other structures that cannot even be seen in conventional X-rays. Using the same dosage of radiation as that of an ordinary X-ray machine, an entire slice of the body can be made visible with about 100 times more clarity with the CAT scan.
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Catheter: A thin, flexible tube . For example, a catheter placed in a vein provides a pathway for giving drugs, nutrients, fluids, or blood products. Samples of blood can also be withdrawn through the catheter.
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Cell: The basic structural and functional unit in people and all living things. Each cell is a small container of chemicals and water wrapped in a membrane .
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Cholangiogram: A radiologic procedure used to look at the gallbladder and bile ducts. See also: Intravenous cholangiogram.
Cholangiography: Radiographic examination of the bile ducts with contrast medium. The contrast medium may be administered orally or injected intravenously or percutaneously (through the skin).
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Cholangitis: Inflammation of the bile duct. From cholangi-, pertaining to a bile duct + -itis, inflammation. See also: Primary sclerosing cholangitis
Cholecystectomy: Surgical removal of the gallbladder. This procedure may be done by laparoscopy or by open surgery. See: Laparoscopic cholecystectomy; Open cholecystectomy.
Cholecystitis: Inflammation of the gallbladder, a complication of gallstones which are formed by cholesterol and pigment (bilirubin) in bile. (Bile is produced in the liver and stored in the gallbladder). Cholecystitis is frequently associated with infection in the gallbladder. Risk factors for cholesterol gallstones include age, obesity, female gender, multiple pregnancies, birth control pills, and heredity. The most common symptom is pain in the upper abdomen. Diagnosis is usually made with ultrasound of the abdomen. Some patients have no symptoms. Patients with mild and infrequent symptoms may consider oral medication to dissolve gallstones. Surgery (standard or laparoscopic) is considered for patients with severe symptoms and for patient with cholecystitis.
Cholecystokinin: Abbreviated CCK. A polypeptide hormone that stimulates the contraction of the gallbladder with release of bile and the secretion of pancreatic enzymes into the small intestine. CCK is secreted by cells lining the upper intestine and by the hypothalamus. Hypothalamic cholecystokinin is a neurotransmitter. Called also pancreozymin.
Cholescintigraphy: A diagnostic test in which a two-dimensional picture of a radiation source in the biliary system is obtained by the use of radioisotopes. Cholescintigraphy is done by nuclear medicine physicians to examine the biliary system and diagnose obstruction of the bile ducts (for example, by a gallstone or a tumor), disease of the gallbladder, and bile leaks. For cholescintigraphy, a radioactive chemical is injected intravenously. The chemical is removed from the blood by the liver, and secreted into the bile that the liver makes. The chemical then goes everywhere that the bile goes-into the bile ducts, the gallbladder, and the intestine. By placing a radiation-sensitive camera over the patient's abdomen, a "picture" of the liver, bile ducts, and gallbladder may be obtained that corresponds to where the radioactive bile has migrated.
Cholesterol: The most common type of steroid in the body, cholesterol has gotten something of a bad name. However, cholesterol is a critically important molecule.
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Chronic: This important term in medicine comes from the Greek chronos, time and means lasting a long time.
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Cirrhosis: An abnormal liver condition characterized by irreversible scarring of the liver. Alcohol and viral hepatitis B and C are among the many causes of cirrhosis. Cirrhosis can cause yellowing of the skin (jaundice), itching, and fatigue. Diagnosis of cirrhosis can be suggested by physical examination and blood tests, and can be confirmed by liver biopsy in some patients. Complications of cirrhosis include mental confusion, coma, fluid accumulation (ascites), internal bleeding, and kidney failure. Treatment of cirrhosis is designed to limit any further damage to the liver as well as complications. Liver transplantation is becoming an important option for patients with advanced cirrhosis.
Colic: An attack of crying and apparent abdominal pain in early infancy. This is a common condition, occurring in about 1 in every 10 babies. Colic is characterized by episodes of irritability, loud crying, and what appears to be abdominal pain with the legs drawn up and the abdomen feeling rigid.
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Colon: The part of the large intestine that runs from the cecum to the rectum as a long hollow tube that serves to remove water from digested food and let the remaining material, solid waste called stool , move through it to the rectum and leave the body through the anus . .
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Common bile duct: The duct that carries bile from the gallbladder and liver into the duodenum (the upper part of the small intestine). The common bile duct is formed by the junction of the cystic duct that comes from the gallbladder and the common hepatic duct that comes from the liver.
Common hepatic duct: The duct formed by the junction of the right hepatic duct (which drains bile from the right half of the liver) and the left hepatic duct (which drains bile from the left half of the liver). The common hepatic duct then joins the cystic duct coming from the gallbladder to form the common bile duct.
Complication: In medicine, an additional problem that arises following a procedure, treatment or illness and is secondary to it. A complication complicates the situation.
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Computerized tomography: Pictures of structures within the body created by a computer that takes the data from multiple X-ray images and turns them in pictures.
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Condition: The term "condition" has a number of biomedical meanings including the following: - An unhealthy state, such as in "this is a progressive condition."
- A state of fitness, such as "getting into condition."
- Something that is essential to the occurrence of something else; essentially a "precondition."
- As a verb: to cause a change in something so that a response that was previously associated with a certain stimulus becomes associated with another stimulus; to condition a person, as in behavioral conditioning.
Contraction: The tightening and shortening of a muscle.
Contrast: Short for "contrast media." Contrast media are X-ray dyes used to provide contrast, for example, between blood vessels and other tissue.
Crohn's disease : A chronic inflammatory disease, primarily involving the small and large intestine, but which can affect other parts of the digestive system as well. It is named for Burrill Crohn, the American gastroenterologist who first described the disease in 1932.
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Cut: An area of severed skin. Wash a cut or scrape it with soap and water, and keep it clean and dry. Putting alcohol, hydrogen peroxide, or iodine into a wound can delay healing, and should be avoided. Seek medical care if you think you might need stitches, as delay can increase the rate of wound infection. If the cut results from a puncture wound through the shoe, there is a high risk of infection, and you should see your healthcare professional. Redness, swelling, increased pain, and pus draining from the wound also indicate an infection that requires professional care.
Cuts: Severed skin. Washing a cut or scrape with soap and water and keeping it clean and dry is all that is required to care for most wounds. Putting alcohol hydrogen peroxide, and iodine into a wound can delay healing and should be avoided. Seek medical care early if you think that you might need stitches. Any delay can increase the rate of wound infection. Any puncture wound through tennis shoes has a high risk of infection and should be seen by your healthcare professional. Any redness, swelling, increased pain, or pus draining from the wound may indicate an infection that requires professional care.
Diagnosis: 1 The nature of a disease ; the identification of an illness. 2 A conclusion or decision reached by diagnosis. The diagnosis is rabies . 3 The identification of any problem. The diagnosis was a plugged IV.
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Diarrhea : A familiar phenomenon with unusually frequent or unusually liquid bowel movements, excessive watery evacuations of fecal material. The opposite of constipation . The word "diarrhea" with its odd spelling is a near steal from the Greek "diarrhoia" meaning "a flowing through." Plato and Aristotle may have had diarrhoia while today we have diarrhea. There are myriad infectious and noninfectious causes of diarrhea.
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Disease: Illness or sickness often characterized by typical patient problems (symptoms) and physical findings (signs). Disruption sequence: The events that occur when a fetus that is developing normally is subjected to a destructive agent such as the rubella (German measles) virus.
Distal: The more (or most) distant of two (or more) things. For example, the distal end of the femur (the thigh bone) is the end down by the knee; the end more distant from the torso. The distal bile duct is the far end of the cystic duct, the end away from the gallbladder. And the distal lymph node in a chain of nodes is the most distant one. The opposite of distal is proximal.
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Distention: The state of being distended, enlarged, swollen from internal pressure.
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Drain: A device for removing fluid from a cavity or wound. A drain is typically a tube or wick.
Duct: A passage or a tube with well-defined walls suitable for the conveyance of air or liquids, as the bile duct and the pancreatic duct.
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Duodenal: Pertaining to the duodenum, part of the small intestine. As in duodenal ulcer or duodenal biliary drainage.
Duodenal biliary drainage: A procedure used to diagnose gallstones when suspicion is high but other tests are negative. A thin tube is passed through a nostril down the throat, through the esophagus and stomach, into the duodenum. Once the tube is in place, a synthetic hormone related to cholecystokinin is injected IV. It causes the gallbladder to contract and squeeze out bile into the duodenum. The bile then is sucked up through the tube and examined for the presence of cholesterol and pigment particles under a microscope. A modification of duodenal biliary drainage involves collection of bile through an endoscope at the time of EGD (esophagogastroduodenoscopy) or ERCP (endoscopic retrograde cholangio-pancreatography).
Duodenum: The first part of the small intestine. The duodenum extends from the pylorus at the bottom of the stomach to the jejunum, the second part of the small intestine. The duodenum is a common site for the formation of peptic ulcers. We often live with words without thinking where they come from or what they originally meant. That is the case for me with the duodenum. For decades, this writer knew the duodenum as a short but troubled sector of the small intestine. Only today did I learn that the duodenum began as the dodeka-daktulon, twelve fingers to the Greeks, who astutely observed that the duodenum is about 12 finger-breadths long. In German, the popular term for duodenum is Zwölffingerdarm, the 12-finger intestine.
Dysfunction: Difficult function or abnormal function.
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Dyspepsia: Dyspepsia refers to a condition ( disease ) in which there are upper abdominal symptoms which may include upper abdominal pain , bloating (a feeling of abdominal fullness without objective abdominal distention ), early satiety (a feeling of unusual fullness with very little intake of food), nausea , or belching . The symptoms often are provoked by eating.
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EGD: Esophagogastroduodenoscopy.
Endoscope: A lighted optical instrument used to get a deep look inside the body and examine organs such as the throat or esophagus. An endoscope can be rigid or flexible.
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Endoscopic ultrasound : Abbreviated EUS. A procedure that combines endoscopy and ultrasound to obtain images and information about the digestive tract and the surrounding tissue and organs. In EUS a small ultrasound transducer is installed on the tip of the endoscope allowing the transducer to get close to the organs inside the body so the resultant ultrasound images are often more accurate and detailed than ones obtained by traditional ultrasound.
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Enzymes: Proteins that act as a catalysts in mediating and speeding a specific chemical reaction .
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ERCP: Endoscopic retrograde cholangiopancreatography.
Esophagus: The tube that connects the pharynx (throat) with the stomach. The esophagus lies between the trachea (windpipe) and the spine. It passes down the neck, pierces the diaphragm just to the left of the midline, and joins the cardiac (upper) end of the stomach. In an adult, the esophagus is about 25 centimeters (10 inches) long. When a person swallows, the muscular walls of the esophagus contract to push food down into the stomach. Glands in the lining of the esophagus produce mucus, which keeps the passageway moist and facilitates swallowing. Also known as the gullet or swallowing tube. From the Greek oisophagos, from oisein meaning to bear or carry + phagein, to eat.
ESWL: Extracorporeal shock wave lithotripsy.
Event: A set of outcomes. Cardiovascular events might include a heart attack and gastrointestinal events a GI bleed. The use of the term "event" in medicine comes from probability theory.
Extracorporeal: Outside the body, in the anatomic sense. As in extracorporeal circulation, extracorporeal dialysis, and extracorporeal shock wave lithotripsy. From extra- + corpus, meaning body.
Eye: The organ of sight. The eye has a number of components. These components include but are not limited to the cornea, iris, pupil, lens, retina, macula, optic nerve, choroid and vitreous.
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Fat: 1 Along with proteins and carbohydrates, one of the three nutrients used as energy sources by the body. The energy produced by fats is 9 calories per gram. Proteins and carbohydrates each provide 4 calories per gram. 2 Total fat; the sum of saturated, monounsaturated and polyunsaturated fats. Intake of monounsaturated and polyunsaturated fats can help reduce blood cholesterol when substituted for saturated fats in the diet. 3 A slang term for obese or adipose. 4 In chemistry, a compound formed from chemicals called fatty acids. These fats are greasy, solid materials found in animal tissues and in some plants. Fats are the major component of the flabby material of a body, commonly known as blubber.
Fats: Plural of the word "fat". See the definition of fat.
Female: The traditional definition of female was "an individual of the sex that bears young" or "that produces ova or eggs". However, things are not so simple today. Female can be defined by physical appearance, by chromosome constitution (see Female chromosome complement), or by gender identification. Female chromosome complement: The large majority of females have a 46, XX chromosome complement (46 chromosomes including two X chromosomes). A minority of females have other chromosome constitutions such as 45,X (45 chromosomes including only one X chromosome) and 47,XXX (47 chromosomes including three X chromosomes).
Fever : Although a fever technically is any body temperature above the normal of 98.6 degrees F. (37 degrees C.), in practice a person is usually not considered to have a significant fever until the temperature is above 100.4 degrees F (38 degrees C.).
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Fistula: An abnormal passageway in the body. The fistula may go from the body surface into a blindpouch or into an internal organ or go between two internal organs.
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Flatulence: Excess gas in the intestinal tract. But excess flatulence is difficult to define without a yardstick to measure the "normal" frequency of gas passages. Symptom-free individuals have recorded approximately 14 passages of gas per 24 hours. From the Latin flastus, meaning blowing, as a breeze or snort.
Fluoroscopy: An x-ray procedure that makes it possible to see internal organs in motion.
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Gallbladder: A pear-shaped organ just below the liver that stores the bile secreted by the liver. During a fatty meal, the gallbladder contracts, delivering the bile through the bile ducts into the intestines to help with digestion. Abnormal composition of bile leads to formation of gallstones, a process termed cholelithiasis. The gallstones cause cholecystitis, inflammation of the gallbladder.
Gallstones : Stones that form when substances in the bile harden. Gallstones can be as small as a grain of sand or as large as a golf ball. There can be just one large stone, hundreds of tiny stones, or any combination.
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Gangrene: The death of body tissue due to the loss of blood supply to that tissue, sometimes permitting bacteria to invade it and accelerate its decay.
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Gastrointestinal: Adjective referring collectively to the stomach and small and large intestines.
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Geiger counter: The most commonly used portable radiation detection and measuring instrument, consisting of a gas-filled tube containing electrodes, between which an electrical voltage but no current flows. When ionizing radiation passes through the tube, a short, intense pulse of current passes from the negative electrode to the positive electrode and is measured or counted. The number of pulses per second measures the intensity of the radiation field. Geiger counters are highly sensitive to beta particles but relatively insensitive to gamma rays and x-rays.
Genes: The basic biological units of heredity . Segments of deoxyribonucleic acid (DNA) needed to contribute to a function.
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Genetic: Having to do with genes and genetic information.
Health: As officially defined by the World Health Organization, a state of complete physical, mental, and social well-being, not merely the absence of disease or infirmity.
Heart: The muscle that pumps blood received from veins into arteries throughout the body. It is positioned in the chest behind the sternum (breastbone; in front of the trachea, esophagus, and aorta; and above the diaphragm muscle that separates the chest and abdominal cavities. The normal heart is about the size of a closed fist, and weighs about 10.5 ounces. It is cone-shaped, with the point of the cone pointing down to the left. Two-thirds of the heart lies in the left side of the chest with the balance in the right chest.
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Heart attack: The death of heart muscle due to the loss of blood supply. The loss of blood supply is usually caused by a complete blockage of a coronary artery, one of the arteries that supplies blood to the heart muscle. Death of the heart muscle, in turn, causes chest pain and electrical instability of the heart muscle tissue.
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Heart disease: Any disorder that affects the heart. Sometimes the term "heart disease" is used narrowly and incorrectly as a synonym for coronary artery disease. Heart disease is synonymous with cardiac disease but not with cardiovascular disease which is any disease of the heart or blood vessels. Among the many types of heart disease, see, for example: Angina; Arrhythmia; Congenital heart disease; Coronary artery disease (CAD); Dilated cardiomyopathy; Heart attack (myocardial infarction); Heart failure; Hypertrophic cardiomyopathy; Mitral regurgitation; Mitral valve prolapse; and Pulmonary stenosis.
Hemoglobin: The oxygen-carrying pigment and predominant protein in the red blood cells . Hemoglobin forms an unstable, reversible bond with oxygen. In its oxygenated state it is called oxyhemoglobin and is bright red. In the reduced state it is called deoxyhemoglobin and is purple-blue.
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Hepatic: Having to do with the liver. Pronounced hi-'pa-tik. From the Latin hepaticus derived from the Greek hepar meaning (not too surprisingly) the liver.
Hepatic duct: A duct that carries bile from the liver into the common bile duct which conveys it to the duodenum (the upper part of the small intestine). There are three hepatic ducts: the right hepatic duct (which drains bile from the right half of the liver); the left hepatic duct (which drains bile from the left half of the liver); and the common hepatic duct (which is formed by the junction of the right and left hepatic ducts).
Hormone: A chemical substance produced in the body that controls and regulates the activity of certain cells or organs.
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Hormone therapy: A form of treatment that takes advantage of the fact that certain cancers depend on hormones to grow. Hormone therapy may include giving hormones to the patient or decreasing the level of hormones in the body.
Ileum: The lowest part of the small intestine , located beyond the duodenum and jejunum , just before the large intestine (the colon ). Pronounced "il-eum" in the US and "eye-leum" in the UK.
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Ileus: Obstruction of the intestine due to it being paralyzed. The paralysis does not need to be complete to cause ileus, but the intestine must be so inactive that it prohibits the passage of food and leads to blockage of the intestine. Ileus commonly follows some types of surgery. It can result also from certain drugs, injuries, and illnesses. Irrespective of the cause, ileus causes constipation and bloating. On listening to the abdomen with a stethoscope, no bowel sounds are heard (because the bowel is inactive). Also called paralytic ileus.
Incision: A cut. When making an incision, a surgeon is making a cut.
Infection: The growth of a parasitic organism within the body. (A parasitic organism is one that lives on or in another organism and draws its nourishment therefrom.) A person with an infection has another organism (a "germ") growing within him, drawing its nourishment from the person.
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Inflammation: A basic way in which the body reacts to infection , irritation or other injury, the key feature being redness, warmth, swelling and pain . Inflammation is now recognized as a type of nonspecific immune response .
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Intestine: The long, tubelike organ in the abdomen that completes the process of digestion. It consists of the small and large intestines.
Intrahepatic: Within the liver.
Intravenous cholangiogram: Abbreviated IVC. A radiologic procedure used primarily to look at the larger bile ducts in the liver and the bile ducts outside the liver. IVC can be used to locate gallstones within the bile ducts and identify other causes of obstruction to the flow of bile. For an IVC, an iodine-containing dye is injected intravenously. The dye is removed from blood by the liver which excretes it into the bile. The dye outlines the bile ducts and any gallstones that may be within them.
Iodine: An essential element in the diet used by the thyroid gland to make thyroid hormones .
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Jaundice: Yellow staining of the skin and sclerae (the whites of the eyes) by abnormally high blood levels of the bile pigment bilirubin . The yellowing extends to other tissues and body fluids. Jaundice was once called the "morbus regius" (the regal disease) in the belief that only the touch of a king could cure it.
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Laparoscopic: 1. Pertaining to the procedure of laparoscopy .
2. Pertaining to a laparoscope , the instrument by which laparoscopy is done.
3. Performed by laparoscopy.
4. Performed with a laparoscope.
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Lithotripsy: A procedure to break a stone into small particles that can be passed in the urine.
Liver: An organ in the upper abdomen that aids in digestion and removes waste products and worn-out cells from the blood. The liver is the largest solid organ in the body. The liver weighs about three and a half pounds (1.6 kilograms). It measures about 8 inches (20 cm) horizontally (across) and 6.5 inches (17 cm) vertically (down) and is 4.5 inches (12 cm) thick.
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Magnetic resonance imaging : A special radiology technique designed to image internal structures of the body using magnetism, radio waves, and a computer to produce the images of body structures. In magnetic resonance imaging (MRI), the scanner is a tube surrounded by a giant circular magnet. The patient is placed on a moveable bed that is inserted into the magnet. The magnet creates a strong magnetic field that aligns the protons of hydrogen atoms, which are then exposed to a beam of radio waves. This spins the various protons of the body, and they produce a faint signal that is detected by the receiver portion of the MRI scanner. A computer processes the receiver information, and an image is produced. The image and resolution is quite detailed and can detect tiny changes of structures within the body, particularly in the soft tissue, brain and spinal cord, abdomen and joints.
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Medication: 1. A drug or medicine. 2. The administration of a drug or medicine. (Note that "medication" does not have the dangerous double meaning of "drug.")
Microscope: An optical instrument that augments the power of the eye to see small objects. The name microscope was coined by Johannes Faber (1574-1629) who in 1628 borrowed from the Greek to combined micro-, small with skopein, to view. Although the first microscopes were simple microscopes, most (if not all) optical microscopes today are compound microscopes.
Microscopic: So small it cannot be seen without the aid of microscope. As opposed to macroscopic (large enough to be seen with naked eye). A tiny tumor is microscopic while a big tumor is macroscopic.
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Mouth: 1. The upper opening of the digestive tract, beginning with the lips and containing the teeth, gums, and tongue. Foodstuffs are broken down mechanically in the mouth by chewing and saliva is added as a lubricant. Saliva contains amylase, an enzyme that digests starch. 2. Any opening or aperture in the body. The mouth in both senses of the word is also called the os, the Latin word for an opening, or mouth. The o in os is pronounced as in hope. The genitive form of os is oris from which comes the word oral.
MRCP: Magnetic resonance cholangiopancreatography, an application of MRI ( magnetic resonance imaging ) to the hepatobiliary and pancreatic system. An MRCP uses an MRI machine with special software to obtain images comparable to the cholangiogram and pancreatogram obtained by the more invasive approach with ERCP (endoscopic retrograde cholangiopancreatography) without the added risks of sedation, pancreatitis , and perforation.
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MRI: Abbreviation and nickname for magnetic resonance imaging. For more information, see: Magnetic Resonance Imaging; Paul C. Lauterbur; Peter Mansfield.
Mucus: A thick slippery fluid produced by the membranes lining certain organs such as the nose, mouth, throat, and vagina. Mucus is the Latin word for "a semifluid, slimy discharge from the nose." Note that mucus is a noun while the adjective is mucous.
Muscle: Muscle is the tissue of the body which primarily functions as a source of power. There are three types of muscle in the body. Muscle which is responsible for moving extremities and external areas of the body is called "skeletal muscle." Heart muscle is called "cardiac muscle." Muscle that is in the walls of arteries and bowel is called "smooth muscle."
Muscular: Having to do with the muscles. Also, endowed with above average muscle development. Muscular system refers to all of the muscles of the body collectively.
Nausea: Nausea is the urge to vomit. It can be brought by many causes including, systemic illnesses, such as influenza, medications, pain, and inner ear disease.
Nostril: One of the openings in the nose that allows air to flow in and out of the nasal cavities. The word nostril comes from the Old English nosu, nose + thyrel, hole = the nose hole.
Nuclear medicine: The branch of medicine concerned with the use of radioisotopes in the diagnosis, management, and treatment of disease. Nuclear medicine uses small amounts of radioactive materials or radiopharmaceuticals, substances that are attracted to specific organs, bones, or tissues. The radiopharmaceuticals used in nuclear medicine emit gamma rays that can be detected externally by special types of cameras: gamma or PET cameras. These cameras work in conjunction with computers used to form images that provide data and information about the area of body being imaged. The amount of radiation from a nuclear medicine procedure is comparable to that received during a diagnostic x-ray.
Obese: Well above ones normal weight. A person has traditionally been considered to be obese if they are more than 20 percent over their ideal weight. That ideal weight must take into account the person's height, age, sex, and build.
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Obesity: The state of being well above one's normal weight.
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Obstruction: Blockage of a passageway. See, for example: Airway obstruction; Intestinal obstruction.
Operation: Although there are many meanings to the word "operation", in medicine it refers to a surgical procedure.
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Oral cholecystogram: Abbreviated OCG. An x-ray procedure for diagnosing gallstones. The patient takes iodine-containing tablets by mouth for one night or two nights in a row. The iodine is absorbed from the intestine into the bloodstream, removed from the blood by the liver, and excreted by the liver into the bile. The iodine, together with the bile, is highly concentrated in the gallbladder. Iodine is used in an OCG because it is dense and radioopaque (stops x-rays). It outlines the gallstones that are radiolucent (x-rays pass through them) and that are usually invisible on x-ray. The failure to visualize the gallbladder on an OCG is evidence for a diseased gallbladder. The OCG is an excellent procedure for diagnosing gallstones when they are strongly suspected but cannot be seen by ultrasound.
Organ: A relatively independent part of the body that carries out one or more special functions. The organs of the human body include the eye, ear, heart, lungs, and liver.
Pain: An unpleasant sensation that can range from mild, localized discomfort to agony. Pain has both physical and emotional components. The physical part of pain results from nerve stimulation. Pain may be contained to a discrete area, as in an injury, or it can be more diffuse, as in disorders like fibromyalgia . Pain is mediated by specific nerve fibers that carry the pain impulses to the brain where their conscious appreciation may be modified by many factors.
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Pancreas: A fish-shaped spongy grayish-pink organ about 6 inches (15 cm) long that stretches across the back of the abdomen, behind the stomach. The head of the pancreas is on the right side of the abdomen and is connected to the duodenum (the first section of the small intestine). The narrow end of the pancreas, called the tail, extends to the left side of the body.
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Pancreatic: Having to do with the pancreas, a spongy, tube-shaped organ about 6 inches long. It is located in the back of the abdomen, behind the stomach. The head of the pancreas is on the right side of the abdomen. It is connected to the duodenum, the upper end of the small intestine. The narrow end of the pancreas, called the tail, extends to the left side of the body.
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Pancreatic cancer: Malignancy of the pancreas. Pancreatic cancer has been called a "silent" disease because early pancreatic cancer usually does not cause symptoms. If the tumor blocks the common bile duct and bile cannot pass into the digestive system, the skin and whites of the eyes may become yellow (jaundiced), and the urine darker as a result of accumulated bile pigment called bilirubin.
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Pancreatitis : Inflammation of the pancreas. Of the many diverse causes of pancreatitis , the most common are alcohol and gallstones .
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Papilla of Vater: See: Ampulla of Vater.
Peritoneum: The membrane that lines the abdominal cavity and covers most of the abdominal organs. (From the Greek peri- meaning around + tonos meaning a stretching = a stretching around).
Peritonitis: Inflammation of the peritoneum (The peritoneum is the tissue layer of cells lining the inner wall of the abdomen and pelvis). Peritonitis can result from infection (such as bacteria or parasites), injury and bleeding, or diseases (such as systemic lupus erythematosus).
Pigment: A substance that gives color to tissue. Pigments are responsible for the color of skin, eyes, and hair.
Pregnancy: The state of carrying a developing embryo or fetus within the female body. This condition can be indicated by positive results on an over-the-counter urine test, and confirmed through a blood test, ultrasound, detection of fetal heartbeat, or an X-ray. Pregnancy lasts for about nine months, measured from the date of the woman's last menstrual period (LMP). It is conventionally divided into three trimesters, each roughly three months long.
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Pregnant: The state of carrying a developing fetus within the body.
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Prevalence: The proportion of individuals in a population having a disease. Prevalence is a statistical concept referring to the number of cases of a disease that are present in a particular population at a given time.
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Primary: First or foremost in time or development. The primary teeth (the baby teeth) are those that come first. Primary may also refer to symptoms or a disease to which others are secondary.
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Pus: A thick whitish-yellow fluid which results from the accumulation of white blood cells (WBCs), liquified tissue and cellular debris. Pus is commonly a site of infection or foreign material in the body.
Radioactive: Emitting energy waves due to decaying atomic nuclei. Radioactive substances are used in medicine as tracers for diagnosis, and in treatment to kill cancerous cells.
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Radiologic: Having to do with radiology.
Recur: To occur again. To return. Any symptom (such as fatigue), any sign (such as a heart murmur), or any disease can recur.
Recurrence: The return of a sign, symptom or disease after a remission. The reappearance of cancer cells at the same site or in another location is, unfortunately, a familiar form of recurrence.
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Red blood cells: The blood cells that carry oxygen. Red cells contain hemoglobin and it is the hemoglobin which permits them to transport oxygen (and carbon dioxide). Hemoglobin, aside from being a transport molecule, is a pigment. It gives the cells their red color (and their name).
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Rupture: A break or tear in any organ (such as the spleen) or soft tissue (such as the achilles tendon). Rupture of the appendix is more likely among uninsured and minority children when they develop appendicitis.
Scan: As a noun, the data or image obtained from the examination of organs or regions of the body by gathering information with a sensing device.
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Scapula: The shoulder blade (or "wingbone"), the familiar flat triangular bone at the back of the shoulder.
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Sclera: The tough white outer coat over the eyeball that covers approximately the posterior five-sixths of its surface. The sclera is continuous in the front of the eye with the cornea and in the back of the eye with the external sheath of the optic nerve.
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Sepsis: Commonly called a "blood stream infection." The presence of bacteria (bacteremia) or other infectious organisms or their toxins in the blood (septicemia) or in other tissue of the body. Sepsis may be associated with clinical symptoms of systemic (bodywide) illness, such as fever , chills, malaise (generally feeling "rotten"), low blood pressure , and mental status changes. Sepsis can be a serious situation, a life threatening disease calling for urgent and comprehensive care.
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Shock: In medicine, shock is a critical condition brought on by a sudden drop in blood flow through the body. There is failure of the circulatory system to maintain adequate blood flow. This sharply curtails the delivery of oxygen and nutrients to vital organs. It also compromises the kidney and so curtails the removal of wastes from the body. Shock can be due to a number of different mechanisms including not enough blood volume (hypovolemic shock) and not enough output of blood by the heart (cardiogenic shock). The signs and symptoms of shock include low blood pressure (hypotension), overbreathing (hyperventilation), a weak rapid pulse, cold clammy grayish-bluish (cyanotic) skin, decreased urine flow (oliguria), and mental changes (a sense of great anxiety and foreboding, confusion and, sometimes, combativeness).
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Sickle cell disease: A genetic blood disease due to the presence of an abnormal form of hemoglobin, namely hemoglobin S . Hemoglobin is the molecule in red blood cells that transports oxygen from the lungs to the farthest reaches of the body.
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Skin: The skin is the body's outer covering. It protects us against heat and light, injury, and infection. It regulates body temperature and stores water, fat, and vitamin D. Weighing about 6 pounds, the skin is the body's largest organ. It is made up of two main layers; the outer epidermis and the inner dermis.
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Small bowel: Another name for the small intestine .
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Small intestine: The part of the digestive tract that extends from the stomach to the large intestine.
Spasm: A brief, automatic jerking movement. A muscle spasm can be quite painful, with the muscle clenching tightly. A spasm of the coronary artery can cause angina. Spasms in various types of tissue may be caused by stress, medication, over-exercise, or other factors.
Stasis: Stasis refers to a stoppage or slowdown in the flow of blood (or other body fluid such as lymph).
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Sternum: Anatomic name for the breast bone, the long flat bone in the upper middle of the front of the chest.
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Stomach: 1. The sac-shaped digestive organ that is located in the upper abdomen, under the ribs. The upper part of the stomach connects to the esophagus, and the lower part leads into the small intestine.
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Surgery: The word "surgery" has multiple meanings. It is the branch of medicine concerned with diseases and conditions which require or are amenable to operative procedures. Surgery is the work done by a surgeon. By analogy, the work of an editor wielding his pen as a scalpel is s form of surgery. A surgery in England (and some other countries) is a physician's or dentist's office.
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Symptom: Any subjective evidence of disease. Anxiety, lower back pain, and fatigue are all symptoms. They are sensations only the patient can perceive. In contrast, a sign is objective evidence of disease. A bloody nose is a sign. It is evident to the patient, doctor, nurse and other observers.
Thalassemia: Not just one disease but rather a complex series of genetic (inherited) disorders all of which involve underproduction of hemoglobin, the indispensable molecule in red blood cells that carries oxygen. The globin part of hemoglobin is made up of 4 polypeptide chains (usually 2 chains of one type and 2 chains of another type of chain). In thalassemia, there is a mutation (change) in one of the types of globin chains. Depending upon which globin chain is affected, the mutation typically leads to underproduction (or absence) of that globin chain, a deficiency of hemoglobin, and anemia.
Therapy: The treatment of disease .
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Throat: The throat is the anterior (front) portion of the neck beginning at the back of the mouth , consisting anatomically of the pharynx and larynx . The throat contains the trachea and a portion of the esophagus .
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Tomography: The process for generating a tomogram , a two-dimensional image of a slice or section through a three-dimensional object. Tomography achieves this remarkable result by simply moving an x-ray source in one direction as the x-ray film is moved in the opposite direction during the exposure to sharpen structures in the focal plane, while structures in other planes appear blurred. The tomogram is the picture; the tomograph is the apparatus; and tomography is the process.
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Transducer: An instrument that converts electrical energy into mechanical energy. A transducer can also act as a transmitter and receiver of ultrasound information.
Triglycerides: The major form of fat. A triglyceride consists of three molecules of fatty acid combined with a molecule of the alcohol glycerol. Triglycerides serve as the backbone of many types of lipids (fats). Triglycerides come from the food we eat as well as from being produced by the body.
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Tumor: An abnormal mass of tissue. Tumors are a classic sign of inflammation, and can be benign or malignant (cancerous). There are dozens of different types of tumors. Their names usually reflect the kind of tissue they arise in, and may also tell you something about their shape or how they grow. For example, a medulloblastoma is a tumor that arises from embryonic cells (a blastoma) in the inner part of the brain (the medulla). Diagnosis depends on the type and location of the tumor. Tumor marker tests and imaging may be used; some tumors can be seen (for example, tumors on the exterior of the skin) or felt (palpated with the hands).
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Twin: One of two children produced in the same pregnancy and born during the same birth process.
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Ultrasound : High-frequency sound waves. Ultrasound waves can be bounced off of tissues using special devices. The echoes are then converted into a picture called a sonogram. Ultrasound imaging, referred to as ultrasonography, allows physicians and patients to get an inside view of soft tissues and body cavities, without using invasive techniques. Ultrasound is often used to examine a fetus during pregnancy. There is no convincing evidence for any danger from ultrasound during pregnancy.
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Uncertainty: You may be uncertain why "uncertainty" deserves a place in a medical dictionary but some would say that uncertainty is a key element in medicine.
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Weight loss: Weight loss is a decrease in body weight resulting from either voluntary (diet, exercise) or involuntary (illness) circumstances. Most instances of weight loss arise due to the loss of body fat, but in cases of extreme or severe weight loss, protein and other substances in the body can also be depleted. Examples of involuntary weight loss include the weight loss associated with cancer, malabsorption (such as from chronic diarrheal illnesses ), and chronic inflammation (such as with rheumatoid arthritis).
White blood cell: One of the cells the body makes to help fight infections. There are several types of white blood cells ( leukocytes ). The two most common types are the lymphocytes and neutrophils (also called polymorphonuclear leukocytes, PMNs, or "polys").
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White blood cell count (leukocyte count): The number of white blood cells (WBCs) in the blood. The WBC is usually measured as part of the CBC ( complete blood count ). White blood cells are the infection-fighting cells in the blood and are distinct from the red (oxygen-carrying) blood cells known as erythrocytes. There are different types of white blood cells, including neutrophils (polymorphonuclear leukocytes ; PMNs), band cells (slightly immature neutrophils), T-type lymphocytes (T cells), B-type lymphocytes (B cells), monocytes, eosinophils, and basophils. All the types of white blood cells are reflected in the white blood cell count. The normal range for the white blood cell count varies between laboratories but is usually between 4,300 and 10,800 cells per cubic millimeter of blood. This can also be referred to as the leukocyte count and can be expressed in international units as 4.3 - 10.8 x 109 cells per liter.
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X-ray: 1. High-energy radiation with waves shorter than those of visible light. X-rays possess the properties of penetrating most substances (to varying extents), of acting on a photographic film or plate (permitting radiography), and of causing a fluorescent screen to give off light (permitting fluoroscopy). In low doses X-rays are used for making images that help to diagnose disease, and in high doses to treat cancer . Formerly called a Roentgen ray. 2. An image obtained by means of X-rays.
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