gabapentin, Neurontin, Gralise

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GENERIC NAME: gabapentin

BRAND NAME: Neurontin, Gralise

DRUG CLASS AND MECHANISM: Gabapentin is an anti-sizure (anti-convulsant) drug that is used for preventing seizures and for treating post-herpetic neuralgia, the pain that follows an episode of shingles. The mechanism of action of gabapentin is not known. Gabapentin structurally resembles the neurotransmitter gamma aminobutyric acid (GABA). (Neurotransmitters are drugs that nerves use to communicate with one another.) It is possible that this similarity is related to gabapentin's mechanism of action. In animal models used for testing the anticonvulsant and analgesic (anti-pain) activities of drugs, gabapentin prevents seizures and reduces pain-related responses. The FDA approved gabapentin in December 1993.

Medically Reviewed by a Doctor on 12/9/2014

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