gabapentin, Neurontin, Gralise

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GENERIC NAME: gabapentin

BRAND NAME: Neurontin, Gralise

DRUG CLASS AND MECHANISM: Gabapentin is an anti-sizure (anti-convulsant) drug that is used for preventing seizures and for treating post-herpetic neuralgia, the pain that follows an episode of shingles. The mechanism of action of gabapentin is not known. Gabapentin structurally resembles the neurotransmitter gamma aminobutyric acid (GABA). (Neurotransmitters are drugs that nerves use to communicate with one another.) It is possible that this similarity is related to gabapentin's mechanism of action. In animal models used for testing the anticonvulsant and analgesic (anti-pain) activities of drugs, gabapentin prevents seizures and reduces pain-related responses. The FDA approved gabapentin in December 1993.

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS:

  • Capsules: 100, 300, and 400 mg.
  • Tablets: 100, 300, 400, 600, and 800 mg.
  • Solution: 250 mg/5 ml

STORAGE: Tablets and capsules should be stored between 15 C to 30 C (59 F to 86 F). Gabapentin solution should be refrigerated between 2 C to 8 C (36 F to 46 F).

PRESCRIBED FOR: Gabapentin is approved for treating seizure disorders and nerve damage from herpes zoster (shingles, postherpetic neuralgia). There are many non-approved uses for gabapentin. These include alcohol withdrawal, cocaine withdrawal, hiccups, restless leg syndrome, hyperhidrosis, headaches, diabetic neuropathy, hot flashes, and fibromyalgia.

Medically Reviewed by a Doctor on 2/11/2014



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