furosemide, Lasix (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

DRUG INTERACTIONS: Administration of furosemide with aminoglycoside antibiotics (for example, gentamicin) or ethacrynic acid (Edecrin, another diuretic) may cause hearing damage. Furosemide competes with aspirin for elimination in the urine by the kidneys. Concomitant use of furosemide and aspirin may, therefore, lead to high blood levels of aspirin and aspirin toxicity. Furosemide also may reduce excretion of lithium (Eskalith, Lithobid) by the kidneys, causing increased blood levels of lithium and possible side effects from lithium. Sucralfate (Carafate) reduces the action of furosemide by binding furosemide in the intestine and preventing its absorption into the body. Ingestion of furosemide and sucralfate should be separated by two hours.

When combined with other antihypertensive drugs there is an increased risk of low blood pressure or reduced kidney function.

Nonsteroidal anti-inflammatory drugs (for example., ibuprofen, indomethacin [Indocin, Indocin-SR]) may interfere with the blood pressure reducing effect of furosemide.

PREGNANCY: There are no adequate studies of furosemide in pregnant women.

NURSING MOTHERS: Furosemide is secreted in breast milk. Nursing mothers should avoid breastfeeding while taking furosemide.

Medically reviewed by Eni Williams, PharmD

Reference: FDA Prescribing Information

Medically Reviewed by a Doctor on 12/10/2014

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Pill Finder Tool

Need help identifying pills and medications?
Use the pill identifier tool on RxList.

Back to Medications Index