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- What is furosemide, and how does it work (mechanism of action)?
- What brand names are available for furosemide?
- Is furosemide available as a generic drug?
- Do I need a prescription for furosemide?
- What are the side effects of furosemide?
- What is the dosage for furosemide?
- Which drugs or supplements interact with furosemide?
- Is furosemide safe to take if I'm pregnant or breastfeeding?
- What else should I know about furosemide?
What is furosemide, and how does it work (mechanism of action)?
Furosemide is a potent diuretic (water pill) that is used to eliminate water and salt from the body. In the kidneys, salt (composed of sodium and chloride), water, and other small molecules normally are filtered out of the blood and into the tubules of the kidney. The filtered fluid ultimately becomes urine. Most of the sodium, chloride and water that is filtered out of the blood is reabsorbed into the blood before the filtered fluid becomes urine and is eliminated from the body. Furosemide works by blocking the absorption of sodium, chloride, and water from the filtered fluid in the kidney tubules, causing a profound increase in the output of urine (diuresis). The onset of action after oral administration is within one hour, and the diuresis lasts about 6-8 hours. The onset of action after injection is five minutes and the duration of diuresis is two hours. The diuretic effect of furosemide can cause depletion of sodium, chloride, body water and other minerals. Therefore, careful medical supervision is necessary during treatment. The FDA approved furosemide in July 1982.
What brand names are available for furosemide?
Is furosemide available as a generic drug?
GENERIC AVAILABLE: Yes
Do I need a prescription for furosemide?
What are the side effects of furosemide?
Common side effects of furosemide are:
Other important side effects include:
- ringing in the ears (tinnitus),
- sensitivity to light (photophobia),
- abdominal pain, and
Increased blood sugar and uric acid levels also may occur.
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