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February 10, 2012

Freckles Glossary of Terms

The following are health and medical definitions of terms that appear in the Freckles article.

Albino: A person with albinism. The term was first applied by the Portuguese to people in West Africa who may have had partial or complete albinism. From the Latin albus for white. See also: Albinism.

Arms: An appendage in anatomy and in clinical trials. See: Arm.

Basal cell carcinoma: The most common type of skin cancer, a disease in which the cancer cells resemble the basal cells of the epidermis, the outer layer of the skin.
See the entire definition of Basal cell carcinoma

Benign: Not cancer. Not malignant. A benign tumor does not invade surrounding tissue or spread to other parts of the body. A benign tumor may grow but it stays put (in the same place).
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Biopsy: The removal of a sample of tissue for purposes of diagnosis. (Many definitions of "biopsy" stipulate that the sample of tissue is removed for examination under a microscope. This may or may not be the case. The diagnosis may be achieved by other means such as by analysis of chromosomes or genes.)
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Bumps: The raised area of a bump or bruise results from blood leaking from these injured blood vessels into the tissues as well as from the body's response to the injury. A purplish, flat bruise that occurs when blood leaks out into the top layers of skin is referred to as an ecchymosis.

Cancer: An abnormal growth of cells which tend to proliferate in an uncontrolled way and, in some cases, to metastasize (spread).
See the entire definition of Cancer

Carcinoma: Cancer that begins in the skin or in tissues that line or cover body organs. For example, carcinoma can arise in the breast, colon, liver, lung, prostate, and stomach.

Cell: The basic structural and functional unit in people and all living things. Each cell is a small container of chemicals and water wrapped in a membrane.
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Cryosurgery: Treatment performed with an instrument that freezes and destroys abnormal tissue.
See the entire definition of Cryosurgery

Curable: Amenable to a cure, capable of being cured, to being healed and made well. Most skin cancers, fortunately, are curable. From the word cure, from the Latin cura meaning care, concern or attention.

Dermatologist: A doctor who specializes in the diagnosis and treatment of skin problems.

Dermatology: 1. The branch of medicine concerned with the diagnosis, treatment, and prevention of diseases of the skin, hair, nails, oral cavity and genitals. 2. Sometimes also, cosmetic care and enhancement.
Dermatology is literally the study of the skin.

Ephelides: The plural of ephelis, a type of freckle. Ephelis and ephelides are among the many medical terms that are rarely, if ever, encountered outside of medicine.

Ephelis: A form of freckle. A flat red or light-brown spot on the skin that typically appears during the sunny months and fades in the winter. They are most often found in people with light complexions and in some families, they are an hereditary (genetic) trait. The regular use of sunscreen during times of sun exposure helps to suppress the appearance of the ephelis-type freckle.
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Epidermis: The upper or outer layer of the two main layers of cells that make up the skin. The epidermis is mostly made up of flat, scale-like cells called squamous cells. Under the squamous cells are round cells called basal cells. The deepest part of the epidermis also contains melanocytes. These cells produce melanin, which gives the skin its color.
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Freckle: A flat circular spot on the skin about the size of the head of a nail that develops after repeated exposure to sunlight, particularly in someone of fair complexion. Freckles may be red, yellow, tan, light-brown, brown, or black. They are always darker than the skin around them since they are due to deposits of the dark melanin, a dark pigment.
See the entire definition of Freckle

Freckles: See: Freckle.

Genetic: Having to do with genes and genetic information.

Genetic disease: A disease caused by an abnormality in an individual's genome.
See the entire definition of Genetic disease

Heredity: Genetic transmission from parent to child.

Inheritance: Not something that is contained in a will, but rather a gene, chromosome or genome that is transmitted from parent to child.
See the entire definition of Inheritance

Keratosis: A localized horny overgrowth of the upper layer of skin such as a callus or wart. Among the common forms of keratosis are actinic keratosis and senile keratosis.

Laser: A powerful beam of light that can produce intense heat when focused at close range. Lasers are used in medicine in microsurgery, cauterization, for diagnostic purposes, etc. For example, lasers are employed in microsurgery to cut tissue and remove tissue.
See the entire definition of Laser

Lentigines: When there is one lentigo, there are usually more lentigines.

Lentigo: A type of freckle that is a small tan, brown, or black spot which tends to be darker than the usual (ephelis-type) freckle and which do not fade in the winter. This kind of spot is referred to as lentigo simplex. Although lentigines may be part of a genetic disorder, for the most part they are just isolated and unimportant spots. (The genetic disorder in which lentigines occur is called the LEOPARD syndrome.)
See the entire definition of Lentigo

Liquid nitrogen: Nitrogen in a liquid state. Liquid nitrogen is supercool -- about 200 degrees Celsius (320 degrees Fahrenheit) below zero -- and is used for cryopreservation, cryosurgery, and cryomedicine.
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Liver: An organ in the upper abdomen that aids in digestion and removes waste products and worn-out cells from the blood. The liver is the largest solid organ in the body. The liver weighs about three and a half pounds (1.6 kilograms). It measures about 8 inches (20 cm) horizontally (across) and 6.5 inches (17 cm) vertically (down) and is 4.5 inches (12 cm) thick.


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Liver disease: Liver disease refers to any disorder of the liver. The liver is a large organ in the upper right abdomen that aids in digestion and removes waste products from the blood.
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Malignant: 1. Tending to be severe and become progressively worse, as in malignant hypertension. 2. In regard to a tumor, having the properties of a malignancy that can invade and destroy nearby tissue and that may spread (metastasize) to other parts of the body.
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Melanin: A skin pigment (substance that gives the skin its color). Dark-skinned people have more melanin than light- skinned people. Melanin also acts as a sunscreen and protects the skin from ultraviolet light.
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Melanoma: The most dangerous form of skin cancer, a malignancy of the melanocyte, the cell that produces pigment in the skin. Melanoma is most common in people with fair skin, but can occur in people with all skin colors. Most melanomas present as a dark, mole-like spot that spreads and, unlike a mole, has an irregular border. The tendency toward melanoma may be inherited, and the risk increases with overexposure to the sun and sunburn.
See the entire definition of Melanoma

Metabolism: The whole range of biochemical processes that occur within an organism. Metabolism consists both of anabolism and catabolism (the buildup and breakdown of substances, respectively). The biochemical reactions are known as metabolic pathways and involve enzymes that transform one substance into another substance, either breaking down a substance or building a new chemical substance. The term is commonly used to refer specifically to the breakdown of food and its transformation into energy.

Mole: 1. In dermatology a mole is a pigmented spot on the skin, Also called a nevus. 2. In gynecology, a mass within the uterus formed of partly developed products of conception.
3. In biochemistry, the molecular weight of a substance. In more technical terms, a mole is the number of atoms in exactly 12 g of carbon-12. Mole in this sense is short for molecular weight.

Nail: In medicine, there are two types of nails. One is just a plain old metal nail used to hold 2 or more pieces of bone together, for example, after a fracture. The other type of nail is the horny plate on the end of the finger or toe. Each nail anatomically has a body, lateral nail folds (on the sides), a lunula (the little moon-shaped feature at the base), and a proximal skin fold (at the base).

Neurofibromatosis: A genetic disorder of the nervous system that primarily affects the development and growth of neural (nerve) cell tissues, causes tumors to grow on nerves, and may produce other abnormalities.
See the entire definition of Neurofibromatosis

Nitrogen: Element number 7, a colorless, odorless, tasteless gas that is biologically important. Nitrogen is a constituent of protein and nucleic acids and is present in all living cells. Nitrogen does not support respiration and is fatal if breathed alone, because of the lack of oxygen. Nitrogen is soluble in the blood and body fluids and, when released as bubbles of gas, can have serious or even fatal consequences.
See the entire definition of Nitrogen

Nose: The external midline projection from the face.
See the entire definition of Nose

Pigment: A substance that gives color to tissue. Pigments are responsible for the color of skin, eyes, and hair.

Pigmentation: The coloring of the skin, hair, mucous membranes, and retina of the eye.
See the entire definition of Pigmentation

Prescription: A physician's order for the preparation and administration of a drug or device for a patient. A prescription has several parts. They include the superscription or heading with the symbol "R" or "Rx", which stands for the word recipe (meaning, in Latin, to take); the inscription, which contains the names and quantities of the ingredients; the subscription or directions for compounding the drug; and the signature which is often preceded by the sign "s" standing for signa (Latin for mark), giving the directions to be marked on the container.

Recur: To occur again. To return. Any symptom (such as fatigue), any sign (such as a heart murmur), or any disease can recur.

Seborrheic keratosis: See: Keratosis, seborrheic.

Skin biopsy: Removal of a piece of skin for the purpose of further examination in the laboratory using a microscope.


See the entire definition of Skin biopsy

Skin color: The color of skin which is complexly determined. Skin color depends on many factors including reddening caused by inflammation, the hemoglobin level in the blood, and the darkening caused by increased deposition of the pigment melanin. Melanin itself is a polymer that comes in two types -- a red-yellow form known as pheomelanin and a black-brown form known as eumelanin.
See the entire definition of Skin color back to top

SPF (sun protection factor): A number on a scale for rating the degree of protection provided by sunscreens. SPF stands for Sun Protection Factor.
See the entire definition of SPF

Stage: As regards cancer, the extent of a cancer, especially whether the disease has spread from the original site to other parts of the body. See also: Staging.

Sunburn: Sunburn is an inflammation of the skin that develops in response to exposure to ultraviolet (UV) radiation from the sun or from tanning beds and booths that emit UV radiation. Sunburn is manifested by reddened, painful skin that may develop blisters.
See the entire definition of Sunburn

Sunscreen: A substance that blocks the effect of the sun's harmful rays. Using lotions that contain sunscreens can reduce the risk of skin cancer, including melanoma.

Superficial: In anatomy, on the surface or shallow. As opposed to deep. The skin is superficial to the muscles. The cornea is on the superficial surface of the eye.
See the entire definition of Superficial

Syndrome: A set of signs and symptoms that tend to occur together and which reflect the presence of a particular disease or an increased chance of developing a particular disease.
See the entire definition of Syndrome

Trait: In genetics, a trait refers to any genetically determined characteristic. In technical terms, a genetic trait is amenable to segregation analysis rather than quantitative analysis.
See the entire definition of Trait

Vitamin A: Vitamin A is retinol. Carotene compounds (found, for example, in egg yolk, butter and cream) are gradually converted by the body to vitamin A (retinol). A form of vitamin A called retinal is responsible for transmitting light sensation in the retina of the eye.
See the entire definition of Vitamin A

Xeroderma: Abnormally dry skin.
See the entire definition of Xeroderma

Xeroderma pigmentosum: A genetic disease characterized by such extraordinary sensitivity to sunlight that it results in the development of skin cancer at a very early age. Children with xeroderma pigmentosum (XP) can only play outdoors safely after nightfall. They have been called midnight children, the children of the dark, the children of the night and, perjoratively, vampire children.
See the entire definition of Xeroderma pigmentosum back to top



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  • Related Diseases & Conditions

    • Skin Cancer
      • Skin cancer is the most common form of cancer in humans. There are three main types of skin cancer; basal cell carcinoma and squamous cell carcinoma (the nonmelanoma skin cancers), and melanoma.
    • Melanoma
      • Melanoma is a type of skin cancer which begins in skin cells called melanocytes and affects more than 53,600 people in the United States each year. These melanocytes can grow together to form benign moles which, after a change in size, shape, or color can be a sign of melanoma. Caused by sun exposure, early detection becomes extremely important to avoid a spread to other areas of the body. Diagnosis is confirmed through a biopsy of the abnormal skin and treatment depends on the extent and characteristics of the patient.
    • Moles
      • Moles are small skin growths that may appear flat or raised and are often tan, brown, black, reddish brown, or skin colored. They are typically about the size of a pencil eraser. There are three types of moles. Monthly skin self-exams are essential in the early detection of abnormal moles and melanomas.
    • Sun-Sensitive Drugs (Photosensitivity to Drugs)
      • Sun sensitivity (photosensitivity) is an inflammation of the skin induced by the combination of medications or substances and sunlight. The affect on the skin is redness, which looks similar to a sunburn. Generally, these reactions are either phototoxic or photoallergic. Phototoxic drugs are more common than photoallergic drugs. Symptoms of phototoxic reactions are a burning and stinging sensation and then redness. Symptoms of photoallergic reactions are itching, redness, swelling, blisters of the affected area. Treatment generally is discontinuation of the medication and topical application of creams.
    • Sunburn (Sun Poisoning)
      • Sunburn is caused by overexposure to UV radiation from the sun. UV rays can also damage the eyes. Repeated overexposure to UV rays also increases the risk for scarring, freckles, wrinkles, and dry skin. Symptoms of sunburn include painful, red, tender, and hot skin. The skin may blister, swell, and peel. Sun poisoning (severe sunburn) include nausea, fever, chills, rapid pulse, dizziness and more. Treatment for sunburn depends upon the severity. Sun protection and sunscreen for an individual's skin type is recommended to decrease the chance of sunburn.
    • Sunscreen
      • Sunscreens are crucial for sun protection. Sun damage to the skin from exposure to ultraviolet rays is a risk factor for skin cancer and melanoma. To avoid sunburn, people should limit sun exposure during the peak hours of 10 a.m. to 3 p.m., wear protective clothing, and use a sunscreen. People with sensitive skin should use a sunscreen with an SPF of 30 or more.
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Freckles

What is sunburn?

Sunburn is an inflammation of the skin that is caused by overexposure to ultraviolet (UV) radiation from the sun. A similar burn can follow overexposure to a "sun" (UV or tanning) lamp. UV radiation can also damage the eyes, although no surface burn is apparent.

Sunburn is a very common condition. In the United States, approximately 30% to 40% of adults and close to 80% of children and adolescents report having at least one sunburn in the preceding year.

Can sunburn cause permanent damage?

Yes. Sunburn early in life increases the risk of developing skin cancer later on. Repeated overexposure to ultraviolet rays can also scar, freckle, dry out, and wrinkle the skin prematurely. In addition, frequent overexposure to ultraviolet rays can increase the risk of developing eye cataracts and macular degeneration, a leading cause of blindness.

What is UV...

Read the Sunburn (Sun Poisoning) article »







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