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fosphenytoin-injection, Cerebyx (cont.)

PRECAUTIONS: Tell your doctor your medical history, especially: any alcohol use, low blood pressure, blood disorders (e.g., anemia, porphyria), thyroid problems (hypothyroid), diabetes, immune disorders (systemic lupus erythematosus), liver or kidney problems, any allergies (especially to phenytoin, phenobarbital, ethosuximide, or carbamazepine). This medication is not recommended for use if you have the following conditions: heart problems (e.g., sinus bradycardia, second and third degree A-V block). This drug may make you dizzy or drowsy; use caution engaging in activities requiring alertness such as driving or using machinery. Avoid alcoholic beverages. Caution is advised when using this drug in the elderly because they may be more sensitive to the effects this drug may have on the heart. This medication is not recommended for use during pregnancy. Consult your doctor for more details. It is not known if this medication passes into breast milk. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Tell your doctor or pharmacist of all prescription and nonprescription drugs you may use, especially: other seizure drugs (e.g., carbamazepine, valproic acid, phenobarbital), "blood thinners" (e.g., warfarin), corticosteroids (e.g., prednisone), hormone replacement therapy (e.g., estrogens), rifamycin antibiotics (e.g., rifampin, rifabutin), heart drugs (e.g., quinidine, amiodarone, nifedipine, digoxin, dopamine), vitamin supplements (e.g., vitamin D, folic acid), azole antifungal drugs (e.g., ketoconazole, itraconazole), anti-ulcer drugs (e.g., cimetidine, omeprazole, sucralfate), antidepressant drugs (e.g., amitriptyline, trazodone, fluoxetine), NSAIDs (e.g., ibuprofen, phenylbutazone), certain diabetes medications (e.g., diazoxide, tolbutamide), sulfa drugs (e.g., sulfamethoxazole), trimethoprim, chloramphenicol, disulfiram, doxycycline, anti-cancer drugs, methadone, chlordiazepoxide, metyrapone, pyrimethamine, xanthines (e.g., theophylline, aminophylline), levodopa, cyclosporine, isoniazid, capecitabine. Also, tell your doctor if you use any of the following drowsiness-causing drugs: sleep aids, sedatives, tranquilizers, anti-anxiety drugs like diazepam, narcotic pain relievers like codeine, psychiatric medicines, muscle relaxants, antihistamines like diphenhydramine. Check the labels carefully on all your medicines (e.g., cough- and-cold preparations) because they may contain drowsiness- causing ingredients. Ask your pharmacist about safe use of those products. This medication may interfere with the effectiveness of birth control pills. Consult your doctor or pharmacist about other forms of birth control. This drug may interfere with certain laboratory tests. Make sure laboratory personnel and your doctors know you use this drug. Do not start or stop any medicine without doctor or pharmacist approval.



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