fosinopril sodium, Monopril (cont.)

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PREPARATIONS: Tablets: 10, 20, and 40 mg

STORAGE: Tablets should be stored between 15-30 C (59-86 F).

DOSING: The recommended adult dose for treating hypertension or heart failure is 10-40 mg once or twice daily. The maximum dose is 80 mg daily. Fosinopril is generally prescribed once daily, although some patients may need two doses per day. Patients with reduced kidney function need lower doses since their kidneys do not eliminate fosinopril from the body as well as normal kidneys. Fosinopril may be taken with or without food.

DRUG INTERACTIONS: Combining fosinopril with potassium supplements, potassium containing salt substitutes, or potassium-conserving diuretics such as amiloride (Moduretic), spironolactone (Aldactone), and triamterene (Dyazide, Maxzide), can lead to dangerously high blood levels of potassium (hyperkalemia) since fosinopril has a tendency to reduce the excretion of potassium. Fosinopril should not be taken at the same time as aluminum or magnesium-based antacids, such as simethicone (Mylanta, Gas-X, etc.) or Maalox since these antacids bind fosinopril and decrease the amount of fosinopril that is absorbed from the intestine. Patients should take antacids and fosinopril at least two hours apart.

Fosinopril can cause an increase in the amount of lithium (Eskalith, Lithobid) in the body in patients taking lithium, sometimes causing lithium-associated side effects.

Medically Reviewed by a Doctor on 5/15/2015

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