fosinopril sodium, Monopril (cont.)

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PRESCRIBED FOR: Fosinopril is used for treating high blood pressure. Its blood pressure lowering effect can be further enhanced by adding a diuretic medication ("water pill") such as hydrochlorothiazide. Fosinopril also is used for the treatment of congestive heart failure, a condition in which the heart is not able to pump enough blood, and fluid collects within the body. In patients with congestive heart failure, the ACE inhibitor class of medications has been shown to reduce symptoms and hospitalization and to improve survival. After a heart attack, ACE inhibitors improve the function of the damaged heart and reduce symptoms and hospitalizations due to congestive heart failure.

SIDE EFFECTS: Fosinopril is generally well tolerated. The most common side effects are:

Sexual dysfunction and abnormal liver tests also occur. Impairment of kidney function has been reported with ACE inhibitors, especially in patients with severe heart failure or kidney disease.

Other important and serious side effects, although rare, include:

  • liver failure,
  • low white blood cell counts (neutropenia) and
  • angioedema (swelling of lips and throat that can obstruct breathing).



PREPARATIONS: Tablets: 10, 20, and 40 mg

STORAGE: Tablets should be stored between 15-30 C (59-86 F).

DOSING: The recommended adult dose for treating hypertension or heart failure is 10-40 mg once or twice daily. The maximum dose is 80 mg daily. Fosinopril is generally prescribed once daily, although some patients may need two doses per day. Patients with reduced kidney function need lower doses since their kidneys do not eliminate fosinopril from the body as well as normal kidneys. Fosinopril may be taken with or without food.

Medically Reviewed by a Doctor on 5/15/2015

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