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- What is fosinopril sodium, and how does it work (mechanism of action)?
- Is fosinopril sodium available as a generic drug?
- Do I need a prescription for fosinopril sodium?
- What are the side effects of fosinopril sodium?
- What is the dosage for fosinopril sodium?
- Which drugs or supplements interact with fosinopril sodium?
- Is fosinopril sodium safe to take if I'm pregnant or breastfeeding?
- What else should I know about fosinopril sodium?
What is fosinopril sodium, and how does it work (mechanism of action)?
Fosinopril is in a class of drugs called angiotensin converting enzyme (ACE) inhibitors. ACE inhibitors are used for treating high blood pressure, heart failure and for preventing kidney failure due to high blood pressure and diabetes. Other ACE inhibitors include enalapril (Vasotec), quinapril (Accupril), captopril (Capoten), ramipril (Altace), benazepril (Lotensin), lisinopril (Zestril, Prinivil), moexipril (Univasc) and trandolapril (Mavik). ACE is an enzyme in blood which controls the formation of angiotensin II, a chemical that circulates in blood and causes constriction of arteries and veins. Constriction of arteries and veins elevates blood pressure. ACE inhibitors inhibit ACE and block the formation of angiotensin II. By blocking the formation of angiotensin II, fosinopril relaxes the arteries and veins and lowers blood pressure. By reducing blood pressure, fosinopril also reduces the work that the heart must do to pump blood through the arteries and veins. This improves the output of blood from the heart especially when the heart is failing. The FDA approved fosinopril in May 1991.
Is fosinopril sodium available as a generic drug?
GENERIC AVAILABLE: Yes
Do I need a prescription for fosinopril sodium?
What are the side effects of fosinopril sodium?
Fosinopril is generally well tolerated. The most common side effects are:
Other important and serious side effects, although rare, include:
- liver failure,
- low white blood cell counts (neutropenia) and
- angioedema (swelling of lips and throat that can obstruct breathing).
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