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GENERIC NAME: FOLIC ACID/NICOTINAMIDE(NIACINAMIDE)/ZINC - ORAL (FOH-lick acid/NICK-oh-TIN-uh-mide/zink)

BRAND NAME(S): Nicomide

Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage | Medical Alert

USES: This combination medication is used to treat certain types of acne (e.g., acne vulgaris, acne rosacea) or other irritated skin conditions. People who have low levels of nicotinamide, zinc, or folic acid in their body may develop, or be at an increased risk of developing, these types of skin conditions.

HOW TO USE: Take this medication by mouth usually once or twice daily, or take as directed by your doctor. Taking this product with food may help to reduce any nausea that may occur due to this medicine. Consult your pharmacist.

SIDE EFFECTS: Nausea or vomiting may occur. If any of these effects persist or worsen, notify your doctor. Tell your doctor immediately if any of these serious side effects occur: stomach pain, yellowing eyes and skin, dark urine, fatigue, fever. An allergic reaction to this product is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Before taking this medication, tell your doctor or pharmacist your medical history, especially of: liver problems (e.g., jaundice), diabetes, blood problems (e.g., pernicious anemia), any allergies. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.




Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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folic acid/nicotinamide(niacinamide)/zinc-oral, Nicomide

Folic acid, B vitamins, and homocysteine

Homocysteine is metabolized (chemically transformed) into methionine and cysteine with the help of the B vitamins; folic acid, B12, and B6 (pyridoxine). Therefore, insufficient amounts of these B vitamins in the body can theoretically hamper the metabolic breakdown of homocysteine, and hence increase its blood levels. High levels of homocysteine in the blood (hyperhomocysteinemia) can damage the inner surface of blood vessels, promote blood clotting, and accelerate atherosclerosis.

The current state of knowledge regarding folic acid, homocysteine, and heart attacks is as follows:

  • The level of blood folate is an important determinant of the blood homocysteine level. Low blood folate levels are associated with high blood levels of homocysteine.
  • Low blood folate is common among individuals who do not take multivitamins, but unusual among those who do.
  • The...

Read the Vitamins & Exercise: Heart Attack Prevention Series article »



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