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There isn't enough information available to know if fo-ti is safe when applied directly the skin.
Special Precautions & Warnings:Children: Fo-ti is POSSIBLY UNSAFE when taken by mouth by children due to concerns that it might cause liver damage. At least one case of liver damage linked with fo-ti use in a 5-year-old child has been reported.
Pregnancy and breast-feeding: Fo-ti is POSSIBLY UNSAFE to take by mouth during pregnancy. Fo-ti contains chemicals that can act like a strong laxative. The chemicals work by stimulating the intestine. Bulk-forming laxatives are a safer choice in pregnancy.
It is also POSSIBLY UNSAFE to use fo-ti if you are breast-feeding. The chemicals that have a laxative effect can pass into breast milk and cause diarrhea in some breast-fed infants.
Not enough is known about the safety of applying fo-ti to the skin during pregnancy or breast-feeding. It's best to avoid using it.
Diabetes: Fo-ti might affect blood sugar levels in people with diabetes. Watch for signs of low blood sugar (hypoglycemia) and monitor your blood sugar closely if you have diabetes and take fo-ti.
Hormone-sensitive conditions such as breast cancer, uterine cancer, ovarian cancer, endometriosis, or uterine fibroids: Fo-ti extract might act like estrogen. If you have any condition that might be made worse by exposure to estrogen, don't use fo-ti.
Liver disease: Fo-ti has been linked to multiple cases of liver problems including hepatitis. There is a concern that fo-ti might make existing liver disease worse.
Surgery: Fo-ti might affect blood sugar levels, so there is concern that it might interfere with blood sugar control during and after surgery. Stop using fo-ti at least 2 weeks before a scheduled surgery.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.