fluvastatin, Lescol, Lescol XL

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

What is the dosage for fluvastatin?

The recommended dose range is 20 to 80 mg daily. Fluvastatin may be given once in the evening or twice daily. It may be taken on an empty or full stomach. Fluvastatin extended release can be administered at anytime of the day. Two 40 mg capsules should not be administered at one time.

Which drugs or supplements interact with fluvastatin?

Cyclosporine and fluconazole (Diflucan) increase blood levels of fluvastatin. Therefore, the dose of fluvastatin should be limited to 20 mg twice daily when patients are also taking cyclosporine or fluconazole.

Gemfibrozil should not be combined with fluvastatin due to increased risk of muscle-related side effects when the two drugs are combined.

Combining fluvastatin with colchicine (Colcrys) or one gram or larger doses of niacin also increases the risk of muscle-related side effects.

Fluvastatin increases the effect of warfarin (Coumadin). Patients taking warfarin should be monitored carefully for toxic effects of warfarin.

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