fluticasone propionate oral inhaler, Flovent (Discontinued), Flovent Diskus, Flovent HFA (cont.)

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Medical and Pharmacy Editor:

PREGNANCY: Adequate studies of fluticasone during pregnancy have not been done. Fluticasone use during pregnancy should be avoided unless the potential benefit justifies the potential but unknown risk to the fetus.

NURSING MOTHERS: It is not known if fluticasone is secreted in breast milk. Other medications in the same class as fluticasone are secreted into breast milk. It is not known whether the small amounts that may appear in the milk affect the infant.

SIDE EFFECTS: The most common side effects of fluticasone are headache, upper respiratory infections, throat irritation, nasal congestion, nasal discharge, and hoarseness or difficulty speaking. Fluticasone may also cause bronchospasms (wheezing). Bronchospasms should be treated with a rescue inhaler.

Oral candidiasis or thrush (a fungal infection) may occur.

High doses of inhaled fluticasone may decrease formation and increase break-down of bone thereby weakening bones and promoting fractures.

Higher doses of fluticasone also may suppress the body's ability to make its own natural glucocorticoid in the adrenal gland. People with suppression of their adrenal glands (which can be diagnosed by a testing performed by doctors) need increased amounts of glucocorticoids, probably by the oral or intravenous route, during periods of high physical stress when glucocorticoids are particularly important.

Inhaled steroids may suppress growth, weaken the immune system, and may increase the risk of glaucoma (increased eye pressure), and cataracts.

Allergic reactions, including swelling of face, throat and tongue, rash, hives, and breathing problems also may occur.

Reference: FDA Prescribing Information

Last Editorial Review: 3/16/2012

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