fluticasone propionate oral inhaler, Flovent (Discontinued), Flovent Diskus, Flovent HFA

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GENERIC NAME: fluticasone propionate oral inhaler

BRAND NAMES: Flovent (Discontinued), Flovent Diskus, Flovent HFA

DRUG CLASS AND MECHANISM: Fluticasone propionate is a man-made steroid of the glucocorticoid family which is related to the naturally-occurring steroid hormone, cortisol or hydrocortisone, produced by the adrenal glands. Glucocorticoid steroids have potent anti-inflammatory actions. When used as an inhaler, fluticasone travels to the airways in the lung. In asthmatic patients, the suppression of inflammation within the airways reduces the spasm of muscle cells that surround the airways as well as the accumulation of fluid and cells that accompanies the inflammation which lead to narrowing of the airways. The narrowing makes it difficult to get air into and out of the lungs. When used in lower doses, very little fluticasone is absorbed into the body. When higher doses are used, fluticasone is absorbed and may cause side effects elsewhere in the body. The FDA approved fluticasone in March 1996.



PREPARATIONS: Inhalation aerosol: 44, 110, and 220 mcg/inhalation. Inhalation Powder (Diskhaler): 50, 100, and 250 mcg/inhalation

STORAGE: Fluticasone should be kept at room temperature, 4-30 C (39-86 F), and the aerosol should be shaken well before each use.

PRESCRIBED FOR: Fluticasone is used for the treatment of asthma in patients 4 years of age old or older who require oral steroid treatment. Fluticasone is not used for acute episodes of asthma; a faster acting dilator of the airways such as albuterol (Ventolin, Proventil, Proventil HFA, AccuNeb, Vospire, ProAir) should be used for acute episodes of asthma.

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