fluticasone propionate oral inhaler, Flovent (Discontinued), Flovent Diskus, Flovent HFA

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GENERIC NAME: fluticasone propionate oral inhaler

BRAND NAMES: Flovent (Discontinued), Flovent Diskus, Flovent HFA

DRUG CLASS AND MECHANISM: Fluticasone propionate is a man-made steroid of the glucocorticoid family which is related to the naturally-occurring steroid hormone, cortisol or hydrocortisone, produced by the adrenal glands. Glucocorticoid steroids have potent anti-inflammatory actions. When used as an inhaler, fluticasone travels to the airways in the lung. In asthmatic patients, the suppression of inflammation within the airways reduces the spasm of muscle cells that surround the airways as well as the accumulation of fluid and cells that accompanies the inflammation which lead to narrowing of the airways. The narrowing makes it difficult to get air into and out of the lungs. When used in lower doses, very little fluticasone is absorbed into the body. When higher doses are used, fluticasone is absorbed and may cause side effects elsewhere in the body. The FDA approved fluticasone in March 1996.



PREPARATIONS: Inhalation aerosol: 44, 110, and 220 mcg/inhalation. Inhalation Powder (Diskhaler): 50, 100, and 250 mcg/inhalation

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