fluticasone (nasal inhaler-spray, Flonase, Veramyst) (cont.)

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DRUG INTERACTIONS: Ritonavir (Norvir) and ketoconazole (Nizoral) may increase the blood concentrations of fluticasone and potentially increase its side effects. Drugs that reduce the action of liver enzymes that breakdown fluticasone should not be combined with fluticasone.

PREGNANCY: Fluticasone has not been adequately evaluated in pregnant women. Fluticasone should be used during pregnancy when it is absolutely necessary.

NURSING MOTHERS: It is not known if fluticasone is secreted in breast milk. Other medications in the same class as fluticasone are secreted into breast milk. Fluticasone should be used only while breastfeeding if it is absolutely necessary. 

SIDE EFFECTS: The most common side effects associated with fluticasone are headache, throat infection, nasal irritation, sneezing, cough, nausea, vomiting. Hypersensitivity reactions such as skin rash, itching, facial swelling, and anaphylaxis may occur. Some children may experience growth suppression when using fluticasone. A bloody nasal discharge (nosebleed) and septum perforation may occur. Fungal infection of the nose and throat, glaucoma, and cataracts are also associated with intranasal fluticasone.

High doses, and rarely normal doses, may suppress the adrenal glands and impair their ability to make natural cortisone. People with such suppression (which can be identified by testing) need increased amounts of cortisone orally or by the intravenous route during periods of high physical stress since higher amounts of cortisone are naturally needed by the body to fight physical stress.

Reference: FDA Prescribing Information


Medically Reviewed by a Doctor on 7/31/2014


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