fluticasone (Flonase, Flonase Allergy Relief)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

  • Medical and Pharmacy Editor: William C. Shiel Jr., MD, FACP, FACR
    William C. Shiel Jr., MD, FACP, FACR

    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

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GENERIC NAME: Fluticasone propionate nasal spray

BRAND NAME: Flonase, Flonase Allergy Relief

DRUG CLASS AND MECHANISM: Fluticasone is a man-made corticosteroid. The exact mechanism of action of fluticasone is not known; however, it stimulates glucocorticoid receptors in humans that produces a potent anti-inflammatory response. Fluticasone also works on multiple cells and mediators that are responsible for the inflammatory symptoms of allergic rhinitis (sneezing, runny nose, etc). The FDA approved fluticasone in October 1994.

PRESCRIBED FOR: Fluticasone is used for the management of nasal symptoms of perennial non-allergic rhinitis in adults and children of 4 years of age and older.

Safe and effective use of fluticasone has not been established for children under the age of 4.

SIDE EFFECTS: Side effects of fluticasone include:

Some children may experience growth suppression from use of inhaled steroids.

PRESCRIPTION: Yes, also available over-the-counter (OTC)

GENERIC AVAILABLE: Yes

PREPARATIONS: Fluticasone propionate nasal spray is available as a 16 gm bottle, providing a total of 120 sprays. Each spray contains 50 mcg of fluticasone propionate.

STORAGE: Fluticasone propionate should be store between 4 C and 30 C (39 F and 86 F).

DOSING:

Prescription:

  • Adults: The recommended dosing is 2 sprays per nostril daily. The maximum dose is 200 mcg/day (4 sprays).
  • Adolescents and Children 4 years of age and older: the recommended dosing is 1 spray per nostril daily that maybe increased to 2 sprays per nostril daily. The maximum dose is 200 mcg/day.
Medically Reviewed by a Doctor on 4/14/2015

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