fluticasone (Flonase, Flonase Allergy Relief)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

  • Medical and Pharmacy Editor: William C. Shiel Jr., MD, FACP, FACR
    William C. Shiel Jr., MD, FACP, FACR

    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

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What is fluticasone propionate nasal inhaler-spray, and how does it work (mechanism of action)?

Fluticasone is a man-made corticosteroid. The exact mechanism of action of fluticasone is not known; however, it stimulates glucocorticoid receptors in humans that produces a potent anti-inflammatory response. Fluticasone also works on multiple cells and mediators that are responsible for the inflammatory symptoms of allergic rhinitis (sneezing, runny nose, etc). The FDA approved fluticasone in October 1994.

What brand names are available for fluticasone propionate nasal inhaler-spray?

Flonase, Flonase Allergy Relief

Is fluticasone propionate nasal inhaler-spray available as a generic drug?

GENERIC AVAILABLE: Yes

Do I need a prescription for fluticasone propionate nasal inhaler-spray?

Yes, also available over-the-counter (OTC)

What are the side effects of fluticasone propionate nasal inhaler-spray?

Side effects of fluticasone include:

Some children may experience growth suppression from use of inhaled steroids.

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What is the dosage for fluticasone propionate nasal inhaler-spray?

Which drugs or supplements interact with fluticasone propionate nasal inhaler-spray?

Ritonavir (Norvir) and ketoconazole (Nizoral, Extina, Xolegel, Kuric) increase fluticasone levels in the body by delaying its metabolism (elimination). It is not clear how important this effect is.

Is fluticasone propionate nasal inhaler-spray safe to take if I'm pregnant or breastfeeding?

There are no adequate studies of fluticasone to determine its safety and effectiveness in pregnant women.

It is not known whether fluticasone enters breast milk; therefore, it is best to be cautious before using it in nursing mothers.

What else should I know about fluticasone propionate nasal inhaler-spray?

What preparations of fluticasone propionate nasal inhaler-spray are available?

Fluticasone propionate nasal spray is available as a 16 gm bottle, providing a total of 120 sprays. Each spray contains 50 mcg of fluticasone propionate.

How should I keep fluticasone propionate nasal inhaler-spray stored?

Fluticasone propionate should be store between 4 C and 30 C (39 F and 86 F).

Reference: FDA Prescribing Information.

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Reviewed on 4/14/2015
References
Reference: FDA Prescribing Information.

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