fluticasone propionate (Cutivate)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

Psoriasis Symptoms, Causes and Treatment

What is fluticasone propionate-topical, and how does it work (mechanism of action)?

Fluticasone propionate is a synthetic (man-made) corticosteroid that is used on the skin (topically). The naturally-occurring corticosteroid is cortisol or hydrocortisone produced by the adrenal gland. Corticosteroids have potent anti-inflammatory actions and also suppress the immune response. Similar drugs include betamethasone dipropionate (Diprolene), clobetasol propionate (Temovate), halobetasol propionate (Ultravate), betamethasone dipropionate (Diprosone), desoximetasone (Topicort), halcinonide (Halog), amcinonide (Cyclocort), triamcinolone acetonide (Kenalog), fluocinolone acetonide (Synalar), hydrocortisone butyrate (Locoid), hydrocortisone valerate (Westcort), and mometasone furoate (Elocon). The FDA approved topical fluticasone propionate in December, 1990.

What brand names are available for fluticasone propionate-topical?

Cutivate

Is fluticasone propionate-topical available as a generic drug?

GENERIC AVAILABLE: Yes

Do I need a prescription for fluticasone propionate-topical?

Yes

What are the side effects of fluticasone propionate-topical?

WARNING Prolonged use or application of topical steroids to large surface areas can depress the ability of the body's adrenal glands to produce corticosteroids. This occurs because some of the fluticasone propionate is absorbed into the body and shuts off the production of the naturally occurring corticosteroids.Abruptly stopping hydrocortisone in these individuals can cause symptoms of corticosteroid insufficiency.

Quick GuidePsoriasis Types, Images, Treatments

Psoriasis Types, Images, Treatments

What is the dosage for fluticasone propionate-topical?

  • Fluticasone is available as cream, lotion, and ointment to apply to the skin.
  • It is usually applied one or two times a day to treat most skin conditions.
  • As with other corticosteroid medicines, treatment should be discontinued when control is achieved.
  • To avoid unwanted side effects, corticosteroid medicines should be used for the shortest duration possible to achieve the desired results.

Is fluticasone propionate-topical safe to take if I'm pregnant or breastfeeding?

It is not known whether topical fluticasone can be excreted into human milk. Since many drugs are excreted into human milk topical fluticasone should be used cautiously in nursing mothers.

What else should I know about fluticasone propionate-topical?

What preparations of fluticasone propionate-topical are available?

  • Topical cream: 0.05%
  • Topical lotion: 0.05%
  • Topical ointment: 0.05%

How should I keep fluticasone propionate-topical stored?

Fluticasone propionate topical preparations should be stored at room temperature between 15 C to 30 C (59 F and 86 F).

REFERENCE: FDA Prescribing Information

Quick GuidePsoriasis Types, Images, Treatments

Psoriasis Types, Images, Treatments

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Reviewed on 9/15/2015
References
REFERENCE: FDA Prescribing Information

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