fluticasone and salmeterol oral inhaler, Advair Diskus, Advair HFA (cont.)
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
PRESCRIBED FOR: Advair Diskus is used for the treatment of asthma or chronic obstructive pulmonary disease (COPD) associated with chronic bronchitis. Its action starts within 30 to 60 minutes and can last more than 12 hours. Advair Diskus is generally not needed in patients whose asthma can be controlled easily with infrequent administration of short acting inhalers. Advair HFA is used for treating asthma in individuals 12 years old or older. Advair Diskus or HFA should not be used to treat acute episodes of asthma or COPD.
Use of long acting agents like salmeterol, an active ingredient in Advair, may increase the risk of asthma-related death. Therefore, Advair should only be used in patients whose asthma is uncontrolled by other agents, and who are using long-term asthma-controlling medications such as an inhaled corticosteroid.
GENERIC AVAILABLE: No
PREPARATIONS: Advair Diskus is an oral inhalation powder available in three different forms containing the same amount of salmeterol, 50 mcg, but differing in the amount of fluticasone propionate. 100/50 provides 100 mcg of fluticasone propionate, 250/50 provides 250 mcg of fluticasone propionate, and 500/50 contains 500 mcg of fluticasone propionate per inspiration.
Advair HFA is an oral aerosol containing 21 mcg of salmeterol combined with 45, 115, or 230 mcg fluticasone.
STORAGE: Advair should be stored at room temperature, 68 F to 77 F (20 C to 25 C). It should be kept away from heat or flames and should not be punctured; it should not be frozen or placed in direct sunlight.
DOSING: The recommended Advair Diskus regimen for asthma in individuals 12 years and older is one inhalation twice daily (morning and evening) approximately 12 hours apart. The lowest effective strength should be used and the maximum dose is 500/50 mcg twice daily. For children 4 to 11 years old the recommended treatment is one inhalation of 100/50 mcg twice daily. The recommended regimen of Advair Diskus for COPD is one inhalation of 250/50 mcg twice daily. Higher doses are not more effective.
Medically Reviewed by a Doctor on 2/11/2015
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