fluticasone furoate nasal spray (Veramyst)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

What is fluticasone-nasal spray, and how does it work (mechanism of action)?

Fluticasone is a synthetic steroid of the glucocorticoid family of drugs that is used for treating allergic conditions involving the nose. Fluticasone mimics the naturally-occurring hormone produced by the adrenal glands, cortisol or hydrocortisone. The exact mechanism of action of fluticasone is unknown. Fluticasone has potent anti-inflammatory actions. It is believed that fluticasone exerts its beneficial effects by inhibiting several types of cells and chemicals involved in allergic, immune and inflammatory responses. When used as a nasal inhaler or spray, the medication goes directly to the lining within the nose, and very little is absorbed into the rest of the body. The FDA approved fluticasone in October 1994.

What brand names are available for fluticasone-nasal spray?

Veramyst

Is fluticasone-nasal spray available as a generic drug?

GENERIC AVAILABLE: Yes

Do I need a prescription for fluticasone-nasal spray?

Yes

What are the side effects of fluticasone-nasal spray?

The most common side effects associated with fluticasone are headache, throat infection, nasal irritation, sneezing, cough, nausea, vomiting. Hypersensitivity reactions such as skin rash, itching, facial swelling, and anaphylaxis may occur. Some children may experience growth suppression when using fluticasone. A bloody nasal discharge (nosebleed) and septum perforation may occur. Fungal infection of the nose and throat, glaucoma, and cataracts are also associated with intranasal fluticasone.

High doses, and rarely normal doses, may suppress the adrenal glands and impair their ability to make natural cortisone. People with such suppression (which can be identified by testing) need increased amounts of cortisone orally or by the intravenous route during periods of high physical stress since higher amounts of cortisone are naturally needed by the body to fight physical stress.

Medically Reviewed by a Doctor on 8/28/2015

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