PREGNANCY AND BREASTFEEDING SAFETY:
- Flurbiprofen is generally avoided during pregnancy.
- Flurbiprofen is excreted in breast milk. To avoid adverse effects in the infant, nursing mothers should decide whether to stop nursing or stop flurbiprofen.
- Flurbiprofen should be stored at room temperature 20 C to 25 C (68 F to 77 F) in a sealed, moisture-free container.
- The recommended dose is 50-100 mg 2 to 4 times daily.
- The maximum daily dose is 300 mg.
- Flurbiprofen should be taken with food to reduce stomach upset.
DRUG CLASS AND MECHANISM:
- Flurbiprofen is a nonsteroidal anti-inflammatory drug (NSAID) effective in treating fever, pain, and inflammation in the body. It is similar to ibuprofen (Motrin or Advil), naproxen (Naprosyn), and others. As a group, NSAIDs are non-narcotic relievers of mild to moderate pain of many causes, including injury, menstrual cramps, arthritis, and other musculoskeletal conditions. They work by reducing the levels of prostaglandins, chemicals that are responsible for pain, fever, and inflammation. Flurbiprofen blocks the enzyme that makes prostaglandins (cyclooxygenase), resulting in lower concentrations of prostaglandins. As a consequence, inflammation, pain and fever are reduced.
- The FDA approved flurbiprofen in October 1988.
REFERENCE: FDA Prescribing Information
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