- What is flurbiprofen, and how does it work (mechanism of action)?
- What brand names are available for flurbiprofen?
- Is flurbiprofen available as a generic drug?
- Do I need a prescription for flurbiprofen?
- What are the uses for flurbiprofen?
- What are the side effects of flurbiprofen?
- What is the dosage for flurbiprofen?
- Which drugs or supplements interact with flurbiprofen?
- Is flurbiprofen safe to take if I'm pregnant or breastfeeding?
- What else should I know about flurbiprofen?
What is flurbiprofen, and how does it work (mechanism of action)?
- Flurbiprofen is a nonsteroidal anti-inflammatory drug (NSAID) effective in treating fever, pain, and inflammation in the body. It is similar to ibuprofen (Motrin or Advil), naproxen (Naprosyn), and others. As a group, NSAIDs are non-narcotic relievers of mild to moderate pain of many causes, including injury, menstrual cramps, arthritis, and other musculoskeletal conditions. They work by reducing the levels of prostaglandins, chemicals that are responsible for pain, fever, and inflammation. Flurbiprofen blocks the enzyme that makes prostaglandins (cyclooxygenase), resulting in lower concentrations of prostaglandins. As a consequence, inflammation, pain and fever are reduced.
- The FDA approved flurbiprofen in October 1988.
What brand names are available for flurbiprofen?
Is flurbiprofen available as a generic drug?
GENERIC AVAILABLE: Yes
Do I need a prescription for flurbiprofen?
What are the uses for flurbiprofen?
- Flurbiprofen is used for the treatment of inflammation and pain caused by rheumatoid arthritis or osteoarthritis, as well as soft tissue injuries, such as tendinitis and bursitis.
What are the side effects of flurbiprofen?
Most patients benefit from flurbiprofen and other NSAIDs with few side effects. However, serious side effects can occur, and generally tend to be dose related. Therefore, it is often desirable to use the lowest effective dose to minimize side effects. The most common side effects of flurbiprofen involve the gastrointestinal system. These are:
- Abdominal burning
- Water retention
- Sensitivity to sunlight
- Serious gastrointestinal bleeding
- Liver toxicity
Other important side effects include:
Flurbiprofen should be avoided by patients with a history of asthma attacks, hives, or other allergic reactions to aspirin or other NSAIDs. Rare but severe allergic reactions have been reported in such individuals.
It also should be avoided by patients with peptic ulcer disease or poor kidney function, since this medication can aggravate both conditions.
Like other NSAIDS flurbiprofen may cause heart attacks and strokes; accumulation of fluid and worsen heart failure; cause or worsen hypertension and kidney failure.
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