fluphenazine (Permitil, Prolixin)

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GENERIC NAME: fluphenazine hydrochloride

BRAND NAME: Permitil, Prolixin

DRUG CLASS AND MECHANISM: Fluphenazine is an oral antipsychotic medication used for the management of schizophrenia. Fluphenazine is one of the older, first-generation piperazine phenothiazine antipsychotic medications. Examples of other phenothiazines include:

Although the exact mechanism of phenothiazine antipsychotics is unknown, scientists believe that they may work by blocking the action of dopamine in the brain. Dopamine is a neurotransmitter (chemical) that nerves use to communicate with one another. Phenothiazine antipsychotics are used when patients do not respond to other antipsychotics.

Medically Reviewed by a Doctor on 12/23/2014

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