FLUOXETINE-ORAL (cont.)
DRUG INTERACTIONS: Certain medications taken with this product could result in serious, possibly fatal, drug interactions. Avoid taking MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, selegiline, tranylcypromine) with or within 2 weeks of starting fluoxetine or at least 5 weeks after stopping it. Also avoid taking thioridazine with this medication or within 5 weeks after stopping treatment. Consult your doctor for more information. This drug should not be used with the following medications because very serious (possibly fatal) interactions may occur: astemizole, terfenadine. If you are currently using any of these medications, tell your doctor or pharmacist before starting fluoxetine. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: certain anti-anxiety drugs (e.g., alprazolam, diazepam, buspirone), other SSRI anti-depressants (e.g., citalopram, sertraline), tricyclic anti-depressants (e.g., amitriptyline, imipramine), other anti-depressant drugs (e.g., nefazodone, trazodone, venlafaxine), anti-seizure drugs (e.g., carbamazepine, phenytoin), atomoxetine, dextromethorphan, certain herbal products (e.g., ayahuasca, St John's wort), isoniazid, lithium, meperidine, drugs to treat migraines (e.g., ergotamine, "triptans" such as sumatriptan), pentazocine, psychiatric medications (e.g., aripiprazole, clozapine, haloperidol, pimozide, risperidone), tramadol, tryptophan, weight loss drugs (e.g., sibutramine, phentermine), drugs removed from your system by certain liver enzymes (CYP 2D6 substrates such as amphetamines, flecainide, metoprolol, propafenone, vinblastine), other drugs which can cause bleeding/bruising (e.g., thrombolytic drugs such as TPA, anticoagulants such as heparin or warfarin, antiplatelet drugs including NSAIDs such as ibuprofen). Low-dose aspirin (usually 81-325 mg per day) for heart attack or stroke prevention should be continued unless your doctor instructs you otherwise. Aspirin is similar to NSAID drugs, and can increase the risk of bleeding in combination with this medication (see above). Discuss the risks and benefits with your doctor. Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (e.g., diphenhydramine), medicine for sleep (e.g., sedatives), muscle relaxants, narcotic pain relievers (e.g., codeine), tranquilizers. Check all prescription and nonprescription medicine labels carefully (e.g., cough-and-cold products, pain relievers/fever reducers) for ingredients which may increase the risk of side effects. Ask your pharmacist about the safe use of those products. Do not start or stop any medicine without doctor or pharmacist approval.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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