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February 10, 2012
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flunarizine-oral capsule, tablet

GENERIC NAME: FLUNARIZINE - ORAL CAPSULE, TABLET (flew-NAIR-eh-zeen)

Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage

USES: This medication is used to prevent migraine headaches. It is effective in reducing the frequency of migraine attacks and to a lesser extent, the severity.

HOW TO USE: Take this medication by mouth exactly as prescribed, usually once a day in the evening. It may take 6 to 8 weeks of continued treatment before the maximum effect of this medication is noted.

SIDE EFFECTS: Drowsiness, weight gain, nausea, heartburn, dry mouth or anxiety may occur as your body adjusts to the medication. If any of these effects continue or become bothersome, inform your doctor. Notify your doctor if you develop: a skin rash, depression, muscle aches, tremor, difficulty moving, abnormal or uncontrolled movements (especially of the face or mouth). If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Tell your doctor if you have: liver disease, movement disorders, Parkinson's disease, a history of depression, any allergies. Use caution operating machinery or engaging in activities requiring alertness. Avoid the use of alcohol while taking this medication since excessive drowsiness can occur. This medication should be used only if clearly needed during pregnancy or while breast-feeding. Discuss the risks and benefits with your doctor.

DRUG INTERACTIONS: Tell your doctor of any over-the-counter or prescription medication you may take, including: sedatives, anti-anxiety medications, muscle relaxants, tranquilizers, anti- seizure medications. Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include confusion, unusual drowsiness, and rapid pulse.

NOTES: This medication is not effective in treating an acute migraine attack. It must be used continuously to prevent migraines from occurring.




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What is a migraine headache?

A migraine headache is a form of vascular headache. Migraine headache is caused by vasodilatation (enlargement of blood vessels) that causes the release of chemicals from nerve fibers that coil around the large arteries of the brain. Enlargement of these blood vessels stretches the nerves that coil around them and causes the nerves to release chemicals. The chemicals cause inflammation, pain, and further enlargement of the artery. The increasing enlargement of the arteries magnifies the pain.

Migraine attacks commonly activate the sympathetic nervous system in the body. The sympathetic nervous system is often thought of as the part of the nervous system that controls primitive responses to stress and pain, the so-called "fight or flight" response, and this activation causes many of the symptoms associated with migraine attacks; for example, the increased sympathetic n...

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