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- What is fludrocortisone-oral, and how does it work (mechanism of action)?
- Is fludrocortisone-oral available as a generic drug?
- Do I need a prescription for fludrocortisone-oral?
- What are the side effects of fludrocortisone-oral?
- What is the dosage for fludrocortisone-oral?
- Which drugs or supplements interact with fludrocortisone-oral?
- Is fludrocortisone-oral safe to take if I'm pregnant or breastfeeding?
- What else should I know about fludrocortisone-oral?
What is fludrocortisone-oral, and how does it work (mechanism of action)?
Fludrocortisone is a man-made oral corticosteroid. It is derived from hydrocortisone, but is more potent than hydrocortisone. The effects of fludrocortisone including its effect on electrolyte balance and carbohydrate metabolism are stronger and prolonged in comparison to hydrocortisone.
Fludrocortisone mimics the actions of aldosterone which is a steroid that is naturally produced by the body. The physiological effects of fludrocortisone are dose dependent. Small oral doses of fludrocortisone cause an increase in blood pressure, sodium retention, and increases urinary potassium excretion. Larger doses of fludrocortisone inhibit the secretion of hormones from the adrenal gland. Fludrocortisone was initially approved by the US Food and Drug Administration (FDA) in 1954. The first generic fludrocortisone tablet was approved by the FDA in March 2002.
Is fludrocortisone-oral available as a generic drug?
GENERIC AVAILABLE: Yes
Do I need a prescription for fludrocortisone-oral?
What are the side effects of fludrocortisone-oral?
Reported side effects include:
- heart problems,
- fluid retention,
- high blood pressure,
- mood or psychiatric disorders,
- trouble sleeping,
- skin problems,
- endocrine disorders,
- (low potassium),
- growth suppression,
- upset stomach,
- stomach ulcers,
- muscle weakness,
- eye problems, and
Fludrocortisone may increase the risk of infections.
Quick GuideLow Blood Pressure (Hypotension): Symptoms, Signs, Causes
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