DRUG INTERACTIONS: This drug should not be used with the following medications because very serious interactions may occur: astemizole, cisapride, terfenadine. If you are currently using any of these medications, tell your doctor or pharmacist before starting fluconazole. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: amitriptyline, certain anti-diabetic drugs (sulfonylureas such as glipizide, glyburide, tolbutamide), certain benzodiazepines (e.g., alprazolam, midazolam, triazolam), "blood thinners" (e.g., warfarin), certain calcium channel blockers (e.g., felodipine, nifedipine), carbamazepine, certain COX-2 inhibitors (e.g., celecoxib, valdecoxib), certain drugs that affect the immune system (e.g., cyclosporine, tacrolimus), eplerenone, phenytoin, rifamycins (e.g., rifabutin, rifampin), theophylline. There are conflicting reports about the effect of this medication with birth control pills. Fluconazole may decrease the effectiveness of combination-type birth control pills. This can result in pregnancy. You may need to use an additional form of reliable birth control while using this medication. Consult your doctor or pharmacist for details. Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include: hallucinations, mental/mood changes.