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FLUCONAZOLE-ORAL (cont.)

PRECAUTIONS: Before taking fluconazole, tell your doctor or pharmacist if you are allergic to it; or to other azole antifungal drugs (e.g., ketoconazole, itraconazole); or if you have any other allergies. Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease. Although uncommon, this drug may make you dizzy; use caution engaging in activities requiring alertness such as driving or using machinery. Limit alcoholic beverages. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. Fluconazole passes into breast milk. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: This drug should not be used with the following medications because very serious interactions may occur: astemizole, cisapride, terfenadine. If you are currently using any of these medications, tell your doctor or pharmacist before starting fluconazole. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: amitriptyline, certain anti-diabetic drugs (sulfonylureas such as glipizide, glyburide, tolbutamide), certain benzodiazepines (e.g., alprazolam, midazolam, triazolam), "blood thinners" (e.g., warfarin), certain calcium channel blockers (e.g., felodipine, nifedipine), carbamazepine, certain COX-2 inhibitors (e.g., celecoxib, valdecoxib), certain drugs that affect the immune system (e.g., cyclosporine, tacrolimus), eplerenone, phenytoin, rifamycins (e.g., rifabutin, rifampin), theophylline. There are conflicting reports about the effect of this medication with birth control pills. Fluconazole may decrease the effectiveness of combination-type birth control pills. This can result in pregnancy. You may need to use an additional form of reliable birth control while using this medication. Consult your doctor or pharmacist for details. Do not start or stop any medicine without doctor or pharmacist approval.




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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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