Flu Vaccine Symptoms, Causes, Treatment - Who should not receive the flu vaccine? on MedicineNet

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February 9, 2012

Flu Vaccination (cont.)

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Who should not receive the flu vaccine?

Those who should avoid the flu vaccine include

  • people who have ever had a severe allergic reaction to eggs;
  • people who have ever had a severe allergic reaction to influenza vaccine;
  • people with a history of Guillain-Barré syndrome (a severe paralytic illness, also called GBS) that occurred after receiving influenza vaccine and who are not at risk for severe illness from influenza should generally not receive vaccine;
  • people under 65 years of age should not receive the high-dose flu shot;
  • people who are under 18 years old or over 64 years old should not receive the intradermal flu shot.
  • If you are sick with a fever when you go to get your flu shot, you should talk to your doctor or nurse about whether or not your shot at a later date. However, you can get a flu shot at the same time you have a respiratory illness without fever or if you have another mild illness.

How effective is the flu shot?

The effectiveness of the flu vaccine is dependent upon the extent of the match between the virus strains used to prepare the vaccine and those viruses in actual circulation. The age and health status of the individual also play a role in determining the effectiveness of the vaccine. Research has shown that when there is a good match between the virus strains chosen for the vaccine and those in circulation, the vaccine prevents influenza illness in approximately 70%-90% of healthy adults under 65 years of age.

A study of children from 1-15 years of age showed that inactivated influenza vaccine was 77%-91% effective in preventing influenza respiratory illness. The effectiveness of the vaccine in preventing respiratory illness in people over 65 years of age is somewhat lower. Among older people who reside in nursing homes, influenza vaccine is most effective in preventing severe illness, secondary complications, and deaths. The vaccine can be 50%-60% effective in preventing influenza-related hospitalization or pneumonia and 80% effective in preventing influenza-related death, although the effectiveness in preventing influenza respiratory illness can be as low as from 30%-40%.


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