- What is flibanserin, and how does it work (mechanism of action)?
- What brand names are available for flibanserin?
- Is flibanserin available as a generic drug?
- Do I need a prescription for flibanserin?
- What are the side effects of flibanserin?
- What is the dosage for flibanserin?
- Which drugs or supplements interact with flibanserin?
- Is flibanserin safe to take if I'm pregnant or breastfeeding?
- What else should I know about flibanserin?
What is flibanserin, and how does it work (mechanism of action)?
Addyi (flibanserin) is an oral drug used for treating low sexual desire in women. The mechanism of action of flibanserin is not completely understood. Flibanserin affects the way the brain works by interfering with communication among the brain's nerves in areas of the brain that control sexual desire and other pleasurable sensations. Nerves communicate with each other by making and releasing chemicals called neurotransmitters. The neurotransmitters travel to other nearby nerves where they attach to receptors on nerves. The attachment of neurotransmitters either stimulates or inhibits the function of the nearby nerves. Flibanserin blocks several of the receptors on nerves including dopamine type 4, and serotonin type 2A, 2B and 2C receptors. It also stimulates serotonin type 1A. How these effects improve sexual desire in women is unknown. Scientists think that flibanserin may regulate areas of the brain that control sexual desire in premenopausal women with reduced sexual interest and desire. The FDA approved flibanserin on August 18, 2015.
What brand names are available for flibanserin?
Is flibanserin available as a generic drug?
GENERIC AVAILABLE: No
Do I need a prescription for flibanserin?
What are the side effects of flibanserin?
Flibanserin may cause low blood pressure and fainting. Patients should lie down and seek medical help if they experience fainting.
Flibanserin causes drowsiness and reduces alertness. Patients should avoid operating machinery, driving, or performing other dangerous activities for at least 6 hours after taking each dose of flibanserin.
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