fingolimod, Gilenya

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

The Effects of Multiple Sclerosis

PRESCRIPTION: Yes

GENERIC AVAILABLE: No

PREPARATIONS: Capsules: 0.5 mg.

STORAGE: Fingolimod should be stored at room temperature, 15 C - 30 C (59 F - 86 F).

DOSING: The recommended dose is 0.5 mg orally once daily, with or without food. Doses higher than 0.5 mg cause more adverse reactions without providing additional benefit.

DRUG INTERACTIONS: The blood levels of fingolimod are increased when combined with ketoconazole (Nizoral, Extina, Xolegel, Kuric). This may increase the incidence of side effects.

Vaccines may be less effective during and up to 2 months after discontinuation of fingolimod treatment. Live attenuated vaccines should not be administered during and for 2 months after fingolimod treatment because of the risk of infection.

When combined with drugs that decrease heart rate (for example, atenolol [Tenormin]) there is an additional 15% reduction of heart rate.

PREGNANCY: Fingolimod has not been adequately studied in pregnant women.

NURSING MOTHERS: It is not known whether fingolimod is secreted in breast milk.

Medically reviewed by Eni Williams, PharmD

Reference: FDA Prescribing Information for Gilenya (fingolimod)

Medically Reviewed by a Doctor on 7/9/2015

Quick GuideMultiple Sclerosis Pictures Slideshow: Causes, Symptoms and Treatment

Multiple Sclerosis Pictures Slideshow: Causes, Symptoms and Treatment
FDA Logo

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

See more info: fingolimod on RxList
RxList Logo

Need help identifying pills and medications?

Use the pill identifier tool on RxList.

Subscribe to MedicineNet's Newsletters

Get the latest health and medical information delivered direct to your inbox!

By clicking Submit, I agree to the MedicineNet's Terms & Conditions & Privacy Policy and understand that I may opt out of MedicineNet's subscriptions at any time.

Health Solutions From Our Sponsors