- What is filgrastim, and how does it work (mechanism of action)?
- What brand names are available for filgrastim?
- Is filgrastim available as a generic drug?
- Do I need a prescription for filgrastim?
- What are the side effects of filgrastim?
- What is the dosage for filgrastim?
- Is filgrastim safe to take if I'm pregnant or breastfeeding?
- What else should I know about filgrastim?
What is filgrastim, and how does it work (mechanism of action)?
Filgrastim is a man-made protein that is similar to the naturally occurring protein, granulocyte-colony stimulating factor (G-CSF). G-CSF is produced in the body by the immune system and stimulates the formation of one type of white blood cell, the neutrophil. Neutrophils take part in the inflammatory reaction. They are responsible for detecting and destroying harmful bacteria and some fungi. Filgrastim is produced by bacteria through the use of genetic engineering and recombinant DNA technology. Filgrastim belongs to a class of drugs called colony-stimulating factors because of their ability to stimulate cells in the bone marrow to multiply and form colonies of new cells. Other CSFs include epoetin alfa (Epogen, Procrit) which stimulates the formation of red blood cells and sargramostim (Leukine) which also stimulates the formation of neutrophils. The FDA approved filgrastim in February 1991.
What brand names are available for filgrastim?
Is filgrastim available as a generic drug?
GENERIC AVAILABLE: No
Do I need a prescription for filgrastim?
What are the side effects of filgrastim?
The most common side effects are:
Other important side effects include:
Uric acid, lactate dehydrogenase, and alkaline phosphatase levels may rise and spontaneously return to normal levels. Heart attacks and abnormal heart rhythm.
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