Fibrates IndexFeatured: Fibrates Main ArticleFibrates (fibric acid derivatives) are a class of medication that lowers blood triglyceride levels. Fibrates modestly effective in increasing HDL cholesterol levels. Examples of fibrates available in the U.S. are gemfibrozil (Lopid) and fenofibrate (Tricor, Fibricor). Side effects, dosing, drug interactions, and pregnancy information should be reviewed prior to taking fibrates.
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Related Diseases & Conditions
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Angina
- Angina is chest pain that is due to an inadequate supply of oxygen to the heart muscle. Angina can be caused by coronary artery disease or spasm of the coronary arteries. EKG, exercise treadmill, stress echocardiography, stress thallium, and cardiac catheterization are important tests used in the diagnosis of angina.
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Pancreatitis
- Pancreatitis is a rare disease in which the pancreas becomes inflamed, occurring when digestive enzymes are activated and begin attacking the pancreas causing damage to the gland. There are two types of pancreatitis, acute and chronic. Most commonly caused by alcohol or gallstones, it can lead to bleeding in the gland, serious tissue damage, infection, and cysts. Enzymes and toxins may then enter the bloodstream and seriously injure organs, such as the heart, lungs, and kidney.
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Cholesterol
- Cholesterol is naturally produced by the body, and is a building block for cell membranes and hormones. Low-density lipoprotein (LDL) cholesterol is the "bad" cholesterol, conversely, high-density lipoprotein (HDL) cholesterol is the "good" cholesterol. High cholesterol treatment includes lifestyle changes (diet and exercise), and medications such as statins, bile acid resins, and fibric acid derivatives.
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Heart Attack
- Heart attack happens when a blood clot completely obstructs a coronary artery supplying blood to the heart muscle. A heart attack can cause chest pain, heart failure, and electrical instability of the heart.
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Metabolic Syndrome
- The main features of metabolic syndrome include insulin resistance, hypertension (high blood pressure), cholesterol abnormalities, and an increased risk for clotting. Patients are most often overweight or obese. Lifestyle modification such as the Mediterranean diet, exercise, and quitting smoking are the preferred treatment of metabolic syndrome.
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Your Cholesterol Profile - In Depth
- Cholesterol is the most common type of steroid in the body. The treatment of elevated cholesterol involves not only diet but also weight loss, regular exercise, and medications. By understanding your cholesterol profile you can better manage your cholesterol levels.
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Heart Attack Prevention Overview
- Heart attacks are the major causes of unexpected, sudden death among men and women. A heart attack is also a significant cause of heart failure. Learn the risk factors for heart attack such as high blood pressure, diabetes, and other heart conditions. Lowering your risk factor, lifestyle changes, and in some cases medication are the most effective way of preventing a heart attack.
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High Cholesterol: Frequently Asked Questions
- Cholesterol occurs naturally in the body. High blood cholesterol levels increase a person's risk of developing heart disease, heart attacks, strokes, TIAs, and more. In addition to medication (fibrates, statins, bile acid sequestrants, and niacin), lifestyle changes can be made to lower blood cholesterol levels
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