Feverfew (Tanacetum parthenium, Chrysanthemum parthenium, Bachelor's Buttons, Featherfew)

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GENERIC NAME: Tanacetum parthenium, Chrysanthemum parthenium

BRAND NAME: Feverfew, Bachelor's Buttons, Featherfew

DRUG CLASS AND MECHANISM: Tanacetum parthenium is an herb. The leaves are used as a natural herbal supplement. Tanacetum parthenium contains parthenolide, which works on serotonin receptors in the brain, giving relief from migraine headaches. Tanacetum parthenium is also believed to have anti-inflammatory, pain relieving, and anti-histamine effects. Check with your health-care professional before using herbs or herbal supplements.



PREPARATIONS: Tanacetum parthenium is available as oral capsules, dried leaf extract, and as a liquid extract. Concentration of Tanacetum parthenium may vary from product-to-product due to multiple manufacturers producing various products.

STORAGE: Due to multiple manufacturers making different forms of Tanacetum parthenium, storage requirements may vary based on individual manufacturer practices.

PRESCRIBED FOR: Tanacetum parthenium is used for the prevention of migraine headaches, rheumatoid arthritis symptoms, and skin irritations (itching, psoriasis) and many other ailments.

DOSING: Migraine headache prevention: Take 50 – 100 mg dried leaf extract by mouth once daily; for other preparations, see manufacturer's directions.

Safe and effective use of Tanacetum parthenium is not established for individuals under the age of 18.

DRUG INTERACTIONS: Tanacetum parthenium should be used with caution with warfarin (Coumadin), clopidogrel (Plavix), and aspirin because Tanacetum parthenium can decrease clotting, increasing bleeding risk from these medications.

Tanacetum parthenium may reduce break down or conversion of drugs in the liver. Examples include omeprazole (Prilosec), lansoprazole (Prevacid), amiodarone (Cordarone), lovastatin (Mevacor), ketoconazole (Nizoral), and itraconazole (Sporanox). Check with your doctor before using this herbal product.

PREGNANCY: Tanacetum parthenium may possibly cause miscarriage in pregnant women; therefore, it is not recommended for use in women who are pregnant or women who may become pregnant.

NURSING MOTHERS: It is not known whether Tanacetum parthenium enters breast milk; It should be avoided by nursing mothers to prevent harm to the newborn.

SIDE EFFECTS: Common side effects of Tanacetum parthenium are oral ulcers and tongue soreness if dried leaves are chewed. It can cause increased heart rates, dizziness, anxiety, sleeplessness, abdominal pain, bloating, nausea, and diarrhea.


MedlinePlus Supplements. Feverfew.

NIH. Feverfew.

Medically Reviewed by a Doctor on 9/19/2014

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