fentanyl transdermal patch, Duragesic (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

DRUG INTERACTIONS: The use of fentanyl with other central nervous system depressants can intensify the effects of fentanyl to depress breathing, depress the brain, sedate, and lower blood pressure.

 Other drugs that may result in slow heart rates in patients when used with fentanyl, and therefore, should be used cautiously include:

Cimetidine (Tagamet) when used with fentanyl can cause confusion, disorientation, or seizures due to impairment in breathing and brain function.

Medically Reviewed by a Doctor on 6/8/2015


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