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- What brand names are available for fentanyl transdermal system?
- Is fentanyl transdermal system available as a generic drug?
- Do I need a prescription for fentanyl transdermal system?
- What are the uses for fentanyl transdermal system?
- What are the side effects of fentanyl transdermal system?
- What is the dosage for fentanyl transdermal system?
- Which drugs or supplements interact with fentanyl transdermal system?
- What else should I know about fentanyl transdermal system?
What is the dosage for fentanyl transdermal system?
- Patches should be applied to a flat, non-irritated area on the upper torso.
- The area of application should be clean and washed with water only prior to application.
- The patch should be applied immediately after removing it from the package and pressed firmly against the skin for 10 to 20 seconds especially around the edges.
- Patches should never be cut or otherwise damaged.
- Doses required to control pain vary widely among patients.
- The recommended dose is 25 to 100 mcg/hour patch applied every 72 hours.
- The manufacturer considers a fentanyl transdermal dose of 100 µg/hour approximately equivalent to 360 mg/day of oral morphine.
Which drugs or supplements interact with fentanyl transdermal system?
The use of fentanyl with other central nervous system depressants can increase the ability of fentanyl to depress breathing, depress the brain, sedate, and lower blood pressure.
Other drugs that may result in slow heart rates in patients when used with fentanyl, and therefore, should be used cautiously include:
- Antipsychotics, for example, Thorazine and Stelazine, haloperidol (Haldol)
- Anxiolytics, for example, diazepam (Valium), lorazepam (Ativan), and zolpidem (Ambien)
- Certain antihistamines, for example, diphenhydramine (Benadryl), and hydroxyzine (Vistaril)
- Barbiturates, for example, phenobarbital (Donnatal)
- Tricyclic antidepressants, for example, amitriptyline (Elavil, Endep) and doxepin (Sinequan), ethanol
- Skeletal muscle relaxants, for example, carisoprodol (Soma), cyclobenzaprine (Flexeril), and baclofen (Lioresal). The use of fentanyl with amiodarone (Cordarone) may result in slow heart rates.
What else should I know about fentanyl transdermal system?
What preparations of fentanyl transdermal system are available?
Transdermal systems labeled as delivering 12, 25, 50, 37.5, 62.5, 75, 87.5, or 100 mcg/hour.
How should I keep fentanyl transdermal system stored?
- Patches should be stored at room temperature below 30 C (86 F). Used patches should be folded in half with the sticky sides together, and then flushed down the toilet.
- Patients must avoid exposing the patches to excessive heat as this promotes the release of fentanyl from the patch and increases the absorption of fentanyl through the skin which can result in fatal overdose.
Reference: FDA Prescribing Information
Quick GuideChronic Pain: Causes and Solutions
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