fenoprofen, Nalfon

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

  • Medical and Pharmacy Editor: Charles Patrick Davis, MD, PhD
    Charles Patrick Davis, MD, PhD

    Charles Patrick Davis, MD, PhD

    Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.

A Guide to Migraine Headaches

DOSING:

The recommended adult dose for mild to moderate pain is 200 mg every 4-6 hours.

Rheumatoid arthritis and osteoarthritis are treated with 300 to 600 mg 3-4 times daily (every 6 to 8 hours). The maximum daily dose is 3200 mg daily.

Fenoprofen should be administered with meals in order to avoid stomach upset.

The safety and effectiveness of this drug in patients under age 18 has not been examined.

DRUG INTERACTIONS: Fenoprofen is associated with several suspected or probable interactions that affect the action of other drugs. The following examples are the most commonly suspected interactions.

  • Fenoprofen may increase the blood levels of lithium (Eskalith, Lithobid) by reducing the excretion of lithium by the kidneys. Increased levels of lithium may lead to lithium toxicity.
  • Fenoprofen may reduce the blood pressure lowering effects of blood pressure medications. This may occur because prostaglandins play a role in the regulation of blood pressure.
  • When NSAIDs are used in combination with methotrexate (Rheumatrex, Trexall) or aminoglycosides (for example, gentamicin) the blood levels of the methotrexate or aminoglycoside may increase, presumably because their elimination from the body is reduced. This may lead to more methotrexate or aminoglycoside-related side effects.
  • Individuals taking oral blood thinners or anticoagulants, for example, warfarin, (Coumadin), should avoid fenoprofen because fenoprofen also thins the blood, and excessive blood thinning may lead to bleeding.
  • Persons who have more than three alcoholic beverages per day are at increased risk of developing stomach ulcers when taking fenoprofen or other NSAIDs.
Medically Reviewed by a Doctor on 8/18/2014

Quick GuideMigraine or Headache? Migraine Symptoms, Triggers, Treatment

Migraine or Headache? Migraine Symptoms, Triggers, Treatment
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