fenofibrate (Antara, Fenoglide, Fibricor, Lipofen, Lofibra, Tricor, Triglide, Trilipix)
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
GENERIC NAME: fenofibrate
BRAND NAME: Antara, Fenoglide, Fibricor, Lipofen, Lofibra, Tricor, Triglide, Trilipix
DRUG CLASS AND MECHANISM: Fenofibrate is a derivative of fibric acid that is used to treat lipid disorders. It is a prodrug, which means that it must be converted to another chemical (fenofibric acid) in the body before it can work.
Fenofibric acid increases the activity of lipoprotein lipase, an enzyme that breaks down triglycerides, a type of fat in the blood. It also affects production, transportation, and storage of triglycerides. Overall benefits of fenofibrate use include a 30%-60% decrease in total blood triglycerides, a modest increase in high density lipoprotein cholesterol (HDL-C, commonly known as "good" cholesterol), and a decrease in low density lipoprotein cholesterol (LDL-C, commonly known as "bad" cholesterol) and total cholesterol.
Fenofibrate products are available in multiple strengths and dosage forms. Fenofibrate formulations are not bioequivalent and are not interchangeable except for generic equivalents. Fenofibrate was approved by the FDA in February 1998.
GENERIC AVAILABLE: Yes
Medically Reviewed by a Doctor on 11/11/2014
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