felodipine, Plendil

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GENERIC NAME: felodipine

BRAND NAME: Plendil

DRUG CLASS AND MECHANISM: Felodipine is an oral calcium- channel blocker (CCB) of the dihydropyridine (DHP) class. Other calcium channel blockers in the DHP class include nifedipine (Procardia, Adalat), amlodipine (Norvasc), nisoldipine (Sular), nicardipine (Cardene), and isradipine (Dynacirc). Calcium is necessary for muscle cells to contract. Felodipine prevents calcium from being released within the muscle cells of the small arteries and thereby causes the muscles to relax and the arteries to dilate or expand. Dilation of arteries reduces blood pressure. Felodipine has little or no effect on the muscles of veins or the heart. Felodipine was approved by the FDA in 1991.

GENERIC AVAILABLE: Yes

PRESCRIPTION: Yes

PREPARATIONS: Tablets (extended Release): 2.5, 5, and10 mg

STORAGE: Tablets should be stored below 86 F (30 C) and should be protected from light and moisture.

PRESCRIBED FOR: Felodipine is used to treat high blood pressure. It may be used alone or in combination with other drugs. Felodipine also is used to treat patients with angina although it is not FDA approved for this use.




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