febuxostat, Uloric (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

DRUG INTERACTIONS: Febuxostat may increase blood levels of mercaptopurine (Purinethol), azathioprine (Imuran), and theophylline (Theo-Dur, Respbid, Slo-Bid, Theo-24, Theolair, Uniphyl, Slo-Phyllin) by reducing their breakdown in the body. Therefore, febuxostat should not be administered with mercaptopurine, azathioprine, and theophylline.

PREGNANCY: There are no adequate studies of febuxostat in pregnant women.

NURSING MOTHERS: It is not known whether febuxostat is excreted in human milk.

SIDE EFFECTS: Common reactions to febuxostat include nausea, rash, joint pain, gout flares, and liver problems. Less common side effects include stroke, heart attack, anemia, hepatitis, hypersensitivity, and weight loss.

REFERENCE: FDA Prescribing information for Uloric

Last Editorial Review: 9/13/2010 11:44:58 AM

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