febuxostat, Uloric

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

Take the Gout Quiz

PRESCRIPTION: Yes

GENERIC AVAILABLE: No

PREPARATIONS: Tablets: 40 and 80 mg

STORAGE: Febuxostat should be stored at room temperature between 15 C to 30 C (59 F to 86 F).

DOSING: The recommended dose is 40 or 80 mg daily. It may be administered with or without food, and it can be taken with antacids. Flares of gout may increase after febuxostat is started as uric acid moves out of tissues. These gout flares may be prevented with non-steroidal anti-inflammatory drugs (for example, indomethacin [Indocin, Indocin-SR]) or colchicine.

DRUG INTERACTIONS: Febuxostat may increase blood levels of mercaptopurine (Purinethol), azathioprine (Imuran), and theophylline (Theo-Dur, Respbid, Slo-Bid, Theo-24, Theolair, Uniphyl, Slo-Phyllin) by reducing their breakdown in the body. Therefore, febuxostat should not be administered with mercaptopurine, azathioprine, and theophylline.

PREGNANCY: There are no adequate studies of febuxostat in pregnant women.

NURSING MOTHERS: It is not known whether febuxostat is excreted in human milk.

Medically reviewed by Eni Williams, PharmD

REFERENCE: FDA Prescribing information for Uloric

Medically Reviewed by a Doctor on 9/11/2015

Quick GuideGout Attack Symptoms, Causes, Treatment, and Diet

Gout Attack Symptoms, Causes, Treatment, and Diet
FDA Logo

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

See more info: febuxostat on RxList
RxList Logo

Need help identifying pills and medications?

Use the pill identifier tool on RxList.

Subscribe to MedicineNet's Arthritis Newsletter

By clicking Submit, I agree to the MedicineNet's Terms & Conditions & Privacy Policy and understand that I may opt out of MedicineNet's subscriptions at any time.

Health Solutions From Our Sponsors