Fatigue

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Fatigue Facts

  • Fatigue (either physical, mental or both) is a symptom that may be difficult for the patient to describe and words like lethargic, exhausted and tired may be used.

  • Taking a careful and complete history is the key to help making the underlying diagnosis of the cause for the symptom of fatigue, However, in about a third of patients the cause is not found and the diagnosis is not known.

  • There are numerous causes of fatigue symptoms. Examples of some treatable causes of fatigue include anemia, diabetes, thyroid disease, heart disease, COPD and sleep disorders (Table).

  • Long lasting complaints of fatigue does not equate to chronic fatigue syndrome. Specific criteria as set by the CDC need to be met to make that particular diagnosis.

Fatigue introduction

Fatigue can be described as the lack of energy and motivation (both physical and mental). This is different than drowsiness, a term that describes the need to sleep. Often a person complains of feeling tired and it is up to the health care professional to distinguish between fatigue and drowsiness, though both can occur at the same time. Aside from drowsiness, other symptoms can be confused with fatigue including shortness of breath with activity and muscle weakness. Again, all these symptoms can occur at the same time. Also, fatigue can be a normal response to physical and mental activity; in most normal individuals it is quickly relieved (usually in hours to about a day, depending on the intensity of the activity) by reducing the activity.

Fatigue is a very common complaint and it is important to remember that it is a symptom and not a disease. Many illnesses can result in the complaint of fatigue and they can be physical, psychological, or a combination of the two.

Often, the symptom of fatigue has a gradual onset and the person may not be aware of how much energy they have lost until they try to compare their ability to complete tasks from one time frame to another. They may presume that their fatigue is due to aging and ignore the symptom. This may lead to a delay in seeking care.

While it is true that depression and other psychiatric issues may be the reason for fatigue, it is reasonable to make certain that there is not an underlying physical illness that is the root cause.

Individuals with fatigue may have three primary complaints; however, it can vary in each person.

  1. There may be lack of motivation or the ability to begin an activity;

  2. the person tires easily once the activity has begun; and

  3. the person has mental fatigue or difficulty with concentration and memory to start or complete an activity.

While fatigue can last for a prolonged period of time, the presence of chronic fatigue is different than chronic fatigue syndrome, which has specific set of two criteria set for by the Centers for Disease Control and Prevention as follows:

  1. Have severe chronic fatigue for at least six months or longer with other known medical conditions (whose manifestation includes fatigue) excluded by clinical diagnosis; and

  2. Concurrently have four or more of the following symptoms:

Other words that a person might use to describe fatigue may include the following:

  • lethargic,

  • listless,

  • lack of energy,

  • tired,

  • worn out,

  • weary,

  • exhausted,

  • malaise, or

  • feeling run down.


Patient Comments

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Fatigue - Causes Question: If known, what was the cause of your fatigue? Please share your experience.
Fatigue - Symptoms Question: What were the signs and symptoms associated with your fatigue?
Fatigue - Diagnosis Question: Discuss the diagnosis process in finding a cause for your fatigue. What was the doctor's diagnosis?
Fatigue - Treatment Question: Depending on your diagnosis, what was the treatment for your fatigue?
Fatigue - Prevention Question: If possible, how do you try to prevent fatigue?
Fatigue - Cause Question: What is the cause of your fatigue?

Why Am I So Tired?

The Many Causes of Fatigue

Medical Author: Charles P. Davis, MD, PhD
Medical Editor: William C. Shiel Jr., MD, FACP, FACR

One of the most common complaints that I hear when taking a history from a patient of a current illness is that the patient says, almost as an afterthought "... and I don't know why I am so tired." In most instances, this complaint is not the main reason that the patient is seeing me. In some instances, "being tired" is mentioned to physicians during a routine checkup after the patient said they have no current health concerns. So, should I as a physician treat the comment like an afterthought and concentrate on the "real reason" the patient is being seen? I could focus on the "real reason" for the visit, but if I skip asking questions about "being tired," I may miss finding out information or clues about the patient's illness and completely overlook a potential diagnosis and treatment for the patient.

Therefore, the first thing to understand about "tired" is what the patient means by the word. Does the patient mean they feel sleepy or fatigued -- they are not the same. Fatigued (tired) describes a lack of energy and motivation, not feeling sleepy (although both can occur together). If the answer is fatigue, the next step is to determine if the fatigue is mental, physical, or both. Now we are beginning to narrow down some clues to the cause of the fatigue, but we (the patient and the doctor) still have a long way to go together.

Fatigue is mainly a symptom and not a disease in itself. The key is for the doctor, with the patient's help, to discover the underlying cause of fatigue. The patient's input is important because accurate answers to the doctor's questions may lead the doctor toward a diagnosis or, at least, may suggest what medical tests may help provide a diagnosis. For example:

  • If the patient says things like "Starting any project is tiring...It is exhausting to get motivated... Concentration takes all of my energy....or... it takes so much effort just to feel normal," the fatigue may have a mental cause.

  • If the patient says things like "I'm exhausted after walking up a flight of stairs...I lose muscle strength after simple repetitive movements..., or I had a viral infection but now I seem unable to get my normal strength back," the fatigue may have a physical cause.

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